Skip to content
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Multi-slice computed tomography: Can it adequately rule out left main coronary disease in patients with an intermediate probability of coronary artery disease?
Cardiology Journal, Volume 17, No. 6, Year 2010
Notification
URL copied to clipboard!
Description
Background: Multi-slice computed tomography (MSCT) is a fast-growing technology that permits a non-invasive, yet reliable, assessment of coronary atherosclerosis. We sought to explore the diagnostic accuracy of MSCT angiography in the detection of significant stenosis of the left main coronary artery (LMCA) in a series of patients with an intermediate pre-test likelihood of coronary artery disease (CAD). Methods: We prospectively enrolled 30 consecutive patients with an intermediate pre-test likelihood of CAD. Patients underwent 64-slice MSCT angiography to detect significant stenosis of the LMCA (defined as ≥ 50% luminal obstruction). They subsequently underwent invasive coronary angiography according to the standard technique. Results: The mean age was 52.7 ± 6.3 years, 24 (80%) being males. Three (10%) patients had significant stenosis of the LMCA by invasive coronary angiography, while four (13.3%) patients were categorized as having significant LMCA stenosis by MSCT coronary angiography. MSCT coronary angiography was able to detect significant LMCA stenosis with a sensitivity of 100%, specificity of 96.3%, positive and negative predictive values of 75% and 100% respectively, and a diagnostic accuracy of 96.7%, with reference to invasive coronary angiography. Conclusions: In patients with an intermediate pre-test likelihood of CAD, MSCT coronary angiography provides a highly accurate diagnostic modality for ruling out significant LMCA stenosis, with reference to invasive coronary angiography. © 2010 Via Medica.
Authors & Co-Authors
Swailam, Salwa
Egypt, Cairo
Faculty of Medicine - Ain Shams University
Abdel-Salam, Zainab
Egypt, Cairo
Faculty of Medicine - Ain Shams University
Emil, Sameh
Egypt, Cairo
Faculty of Medicine - Ain Shams University
Nabil, Hazem
Egypt, Cairo
Faculty of Medicine - Ain Shams University
Nammas, Wail M.
Egypt, Cairo
Faculty of Medicine - Ain Shams University
Statistics
Citations: 5
Authors: 5
Affiliations: 1
Identifiers
ISSN:
18975593