Skip to content
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Prospective cohort study of influenza vaccine effectiveness among healthcare personnel in Lima, Peru: Estudio Vacuna de Influenza Peru, 2016-2018
Influenza and other Respiratory Viruses, Volume 14, No. 4, Year 2020
Notification
URL copied to clipboard!
Description
Background: The Estudio Vacuna de Influenza Peru (VIP) cohort aims to describe the frequency of influenza virus infection, identify predictors of vaccine acceptance, examine the effects of repeated influenza vaccination on immunogenicity, and evaluate influenza vaccine effectiveness among HCP. Methods: The VIP cohort prospectively followed HCP in Lima, Peru, during the 2016-2018 influenza seasons; a fourth year is ongoing. Participants contribute blood samples before and after the influenza season and after influenza vaccination (for vaccinees). Weekly surveillance is conducted to identify acute respiratory or febrile illnesses (ARFI). When an ARFI is identified, participants self-collect nasal swabs that are tested for influenza viruses by real-time reverse transcriptase-polymerase chain reaction. Influenza vaccination status and 5-year vaccination history are ascertained. We analyzed recruitment and enrollment results for 2016-2018 and surveillance participation for 2016-2017. Results: In the first 3 years of the cohort, VIP successfully contacted 92% of potential participants, enrolled 76% of eligible HCP, and retained >90% of participants across years. About half of participants are medical assistants (54%), and most provide “hands-on” medical care (76%). Sixty-nine percent and 52% of participants completed surveillance for >70% of weeks in years 1 and 2, respectively. Fewer weeks of completed surveillance was associated with older age (≥50 years), being a medical assistant, self-rated health of fair or poor, and not receiving the influenza vaccine during the current season (P-values <.05). Conclusions: The VIP cohort provides an opportunity to address knowledge gaps about influenza virus infection, vaccination uptake, effectiveness and immunogenicity among HCP. © 2020 The Authors. Influenza and Other Respiratory Viruses Published by John Wiley & Sons Ltd.
Authors & Co-Authors
Arriola, Carmen
United States, Atlanta
Centers for Disease Control and Prevention
Romero, Candice
Peru, Lima
Naval Medical Research Unit No. 6
Veguilla, Vic
United States, Atlanta
Centers for Disease Control and Prevention
Levine, Min Z.
United States, Atlanta
Centers for Disease Control and Prevention
Silva, María E.
Peru, Lima
Naval Medical Research Unit No. 6
Dawood, Fatimah S.
United States, Atlanta
Centers for Disease Control and Prevention
Katz, Mark A.
Israel, Tel Aviv-yafo
Clalit Health Services
Ticona, Eduardo
Peru, Lima
Hospital Nacional Dos de Mayo
Bravo Paredes, Eduar Alban
Peru, Lima
Universidad Peruana Cayetano Heredia
Martín, Emily Toth
United States, Ann Arbor
University of Michigan School of Public Health
Tinoco, Yeny O.
Peru, Lima
Naval Medical Research Unit No. 6
Azziz-Baumgartner, Eduardo
United States, Atlanta
Centers for Disease Control and Prevention
Thompson, Mark G.
United States, Atlanta
Centers for Disease Control and Prevention
Sambhara, Suryaprakash R.
Unknown Affiliation
Gangappa, Shivaprakash
Unknown Affiliation
Mores, Christopher N.
Unknown Affiliation
Statistics
Citations: 5
Authors: 16
Affiliations: 10
Identifiers
Doi:
10.1111/irv.12737
ISSN:
17502640
Research Areas
Health System And Policy
Study Design
Cohort Study
Study Approach
Quantitative