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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Prevalence of chronic kidney disease in hypertensive patients in ghana
Renal Failure, Volume 33, No. 4, Year 2011
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Description
Chronic kidney disease (CKD) is common in tropical Africa although there are few data on the prevalence of this disorder. Therefore we initiated a multicenter screening study to identify the prevalence and staging of CKD in 712 patients with known hypertension in four polyclinics in Accra, Ghana. We measured estimated glomerular filtration rate by the six-variable modification of diet in renal disease equation and proteinuria by the protein/creatinine ratio. All the subjects studied were Ghanaian. Of the 712 patients studied, the median age was 59 years (range 19-90 years) and 560 (78.7%) of the patients were female. The mean duration of hypertension was 4 years (range 0.1-50). The overall prevalence of CKD was 46.9% (95% CI: 43.2-50.7%); 19.1% had CKD stages 1-2 and 27.8% had CKD stages 3-5. There was no difference in age between patients with or without CKD (p=0.12). The overall prevalence of proteinuria was 28.9% (95% CI: 25.6-32.4%); 14.7% of subjects had preexisting diabetes mellitus and their prevalence of CKD (55%; 95% CI: 42.4-62.2) did not differ from those without diabetes (46%; 95% CI: 41.9-50.0, p=0.133). CKD is common in hypertensive patients in Ghana, with a prevalence of 46.9%. This provides justification for the inclusion of this group in CKD screening programs in Ghana. © 2011 Informa Healthcare USA, Inc.
Authors & Co-Authors
Osafo, Charlotte
Ghana, Accra
University of Ghana
Mate-Kole, Michael O.
Ghana, Accra
University of Ghana
Affram, Kwame O.
Ghana, Accra
University of Ghana
Adu, D. A.
United Kingdom, Birmingham
Queen Elizabeth Hospital Birmingham
Statistics
Citations: 65
Authors: 4
Affiliations: 2
Identifiers
Doi:
10.3109/0886022X.2011.565140
ISSN:
0886022X
e-ISSN:
15256049
Research Areas
Health System And Policy
Noncommunicable Diseases
Study Design
Cross Sectional Study
Study Locations
Ghana
Participants Gender
Female