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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
biochemistry, genetics and molecular biology
Abdominal obesity has the highest impact on metabolic profile in an overweight African population
Annals of Human Biology, Volume 39, No. 6, Year 2012
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Description
Aim: The aim of this study was to determine the association between different anthropometric parameters and metabolic profile in an overweight, adult, black Kenyan population. Methods: An opportunity sample of 245 overweight adult Kenyans (body mass index (BMI) ≥ 25 kg/m2) was analysed. A score of metabolic profile (metabolic Z-score) was constructed on the basis of levels of plasma lipids, blood pressure, blood glucose and serum insulin. Linear regressions using metabolic Z-score as outcome and six anthropometric variables (waist circumference (WC), hip circumference, visceral adipose tissue (VAT), abdominal subcutaneous adipose tissue, arm fat area and arm muscle area) separately as independent variables were carried out. Results: Mean age of study participants was 42.1 years (SD = 9.6) and 26.5% of the participants were men. The median BMI was 28.6 kg/m2 (Q1 = 26.3; Q3 = 31.3). Of the six anthropometric variables tested, WC and VAT thickness had the strongest negative association with the metabolic profile (β = 0.17 (0.09; 0.24) and 0.15 (0.08; 0.23), respectively). Conclusions: WC and VAT thickness were the strongest anthropometric predictors for the metabolic profile in overweight adult Kenyans. WC is useful in clinical practice for the diagnosis of metabolically unhealthy fat accumulation in an African setting. © Informa UK, Ltd.
Authors & Co-Authors
Handlos, Line Neerup
Denmark, Copenhagen
Københavns Universitet
Witte, Daniel R.
Denmark, Herlev
Steno Diabetes Center Copenhagen
Mwaniki, David Lemmy
Kenya, Nairobi
Kenya Medical Research Institute
Boit, M. K.
Kenya, Nairobi
Kenyatta University
Kilonzo, B.
Kenya, Nairobi
Kenya Medical Research Institute
Friis, Henrik M.U.
Denmark, Copenhagen
Københavns Universitet
Hansen, Andreas W.
Denmark, Copenhagen
Statens Institut for Folkesundhed
Borch-Johnsen, Knut
Denmark, Odense
Syddansk Universitet
Tetens, I.
Denmark, Lyngby
Technical University of Denmark
Christensen, Dirk Lund
Denmark, Copenhagen
Københavns Universitet
Denmark, Herlev
Steno Diabetes Center Copenhagen
Statistics
Citations: 10
Authors: 10
Affiliations: 7
Identifiers
Doi:
10.3109/03014460.2012.720279
e-ISSN:
14645033
Research Areas
Noncommunicable Diseases
Study Design
Cross Sectional Study
Participants Gender
Male