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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
immunology and microbiology
Pathomorphological and immunohistological findings in cattle experimentally infected with rinderpest virus isolates of different pathogenicity
Veterinary Microbiology, Volume 44, No. 2-4, Year 1995
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Description
Experimental infection of nine cattle with seven rinderpest virus strains of different pathogenicity resulted in significant variations of clinical signs, morphological lesions and distribution of viral antigen in tissues. The severity of clinical disease was correlated with the extent of tissue alterations and the amount of immunohistologically detectable viral antigen. Both mild and virulent strains of rinderpest share essentially the same tissue tropisms in vivo, i.e. epithelio- and lympho-tropism. However, rinderpest virus isolates of higher pathogenicity showed a more rapid and wider distribution with more extensive lesions than milder strains, which probably accounts for the higher mortality. © 1995.
Authors & Co-Authors
Wohlsein, Peter
Germany, Hannover
Tierärztliche Hochschule Hannover
Wamwayi, Henry M.
United Kingdom, Surrey
The Pirbright Institute
Kenya, Nairobi
Kenya Agricultural Research Institute
Trautwein, Gerhard
Germany, Hannover
Tierärztliche Hochschule Hannover
Pohlenz, J.
Germany, Hannover
Tierärztliche Hochschule Hannover
Liess, Bernd
Germany, Hannover
Tierärztliche Hochschule Hannover
Barrett, Thomas
United Kingdom, Surrey
The Pirbright Institute
Statistics
Citations: 42
Authors: 6
Affiliations: 3
Identifiers
Doi:
10.1016/0378-1135(95)00007-W
ISSN:
03781135