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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
Alkylbenzoquinones with antiproliferative effect against human cancer cell lines from stem of Ardisia kivuensis
Phytochemistry Letters, Volume 4, No. 3, Year 2011
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Description
Two new alkylbenzoquinone derivatives, named as ardisiaquinone J (1) and K (2) were isolated from the MeOH extract of the stem of Ardisia kivuensis Taton (Myrsinaceae), together with the known lupeol and β-sitosterol. Their structures were elucidated on the basis of spectroscopic analysis and comparison with authentic samples. The new compounds exhibited considerable antiproliferative activity against Ishikawa, HeLa, MCF7 and A431 cell lines with IC50 values between 6.64 and 15.40 μM. In addition, compound 2 exerted a moderate free radical scavenging effect on DPPH-assay. © 2011 Phytochemical Society of Europe.
Authors & Co-Authors
Ndonsta, Blanche L.
Cameroon, Dschang
University of Dschang
Tatsimo, Simplice Joel Ndendoung
Cameroon, Maroua
Université de Maroua
Csupor, Dezső O.
Hungary, Szeged
Szegedi Tudományegyetem Szte
Forgó, Péter
Hungary, Szeged
Szegedi Tudományegyetem Szte
Berkecz, Robert
Hungary, Szeged
Szegedi Tudományegyetem Szte
Berényi, Ágnes
Hungary, Szeged
Szegedi Tudományegyetem Szte
Téné, Mathieu
Cameroon, Dschang
University of Dschang
Molnár, Judit
Hungary, Szeged
Szegedi Tudományegyetem Szte
Zupkó, István
Hungary, Szeged
Szegedi Tudományegyetem Szte
Hohmann, Judit
Hungary, Szeged
Szegedi Tudományegyetem Szte
Tané, Pierre
Cameroon, Dschang
University of Dschang
Statistics
Citations: 18
Authors: 11
Affiliations: 3
Identifiers
Doi:
10.1016/j.phytol.2011.04.003
e-ISSN:
18767486
Research Areas
Cancer