Skip to content
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
biochemistry, genetics and molecular biology
The CEPH consortium linkage map of human chromosome 1
Genomics, Volume 9, No. 4, Year 1991
Notification
URL copied to clipboard!
Description
This paper describes the Centre d'Etude du Polymorphisme Humain (CEPH) consortium linkage map of human chromosome 1. The map contains 101 loci defined by genotypes generated from CEPH family DNAs with 146 different contributions from 11 laboratories. A total of 58 loci are uniquely placed on the map with likelihood support of at least 1000:1. The map extends from loci in the terminal bands of both chromosome arms (locus D1Z2 in 1p36.3 and D1S68 in 1q44) and is anchored at the centromere by the D1Z5 α-satellite polymorphism. With the exception of a single locus, the remaining loci are arrayed on the fixed map in short intervals and their possible locations are indicated. Multipoint linkage analyses provided estimates that the male, female, and sex-averaged maps extend for 308, 478, and 390 cM, respectively. The sex-averaged map contains only four intervals > 15 cM, and the mean genetic distance between the 58 uniquely placed loci is 6.7 cM. © 1991.
Authors & Co-Authors
Dracopoli, Nicholas C.
United States, Cambridge
Massachusetts Institute of Technology
O'Connell, Peter
United States, Salt Lake City
University of Utah Health Sciences
Elsner, Tami I.
United States, Salt Lake City
University of Utah Health Sciences
Lalouel, Jean Marc
United States, Salt Lake City
University of Utah Health Sciences
White, Raymond L.
United States, Salt Lake City
University of Utah Health Sciences
Buetow, Kenneth H.
United States, Philadelphia
Fox Chase Cancer Center
Nishimura, Darryl Y.
United States, Iowa City
University of Iowa
Murray, Jeffrey Clark
United States, Iowa City
University of Iowa
Helms, Cynthia
United States, St. Louis
Washington University in St. Louis
Mishra, Santosh K.
United States, St. Louis
Washington University in St. Louis
Donis-Keller, Helen
United States, St. Louis
Washington University in St. Louis
Hall, Jeffrey M.
United States, Berkeley
University of California, Berkeley
Lee, Ming K.
United States, Berkeley
University of California, Berkeley
King, Mary Claire
United States, Berkeley
University of California, Berkeley
Attwood, John
United Kingdom, London
University College London
Morton, Newton E.
United Kingdom, Southampton
University of Southampton
Robson, Elizabeth B.
United Kingdom, London
University College London
Mahtani, Melanie
United States, Stanford
Stanford University School of Medicine
Willard, Huntington F.
United States, Stanford
Stanford University School of Medicine
Royle, Nicola J.
United Kingdom, Leicester
University of Leicester
Patel, Ila
United Kingdom, Leicester
University of Leicester
Jeffreys, Alec J.
United Kingdom, Leicester
University of Leicester
Verga, Vera
South Africa, Tygerberg
South African Medical Research Council
South Africa, Johannesburg
University of the Witwatersrand
Jenkins, Trefor
South Africa, Tygerberg
South African Medical Research Council
South Africa, Johannesburg
University of the Witwatersrand
Weber, James L.
United States, Marshfield
Marshfield Clinic
Mitchell, Anna L.
United States, New Haven
Yale School of Medicine
Bale, Allen E.
United States, New Haven
Yale School of Medicine
Statistics
Citations: 27
Authors: 27
Affiliations: 14
Identifiers
Doi:
10.1016/0888-7543(91)90362-I
ISSN:
08887543
e-ISSN:
10898646
Research Areas
Genetics And Genomics
Participants Gender
Male
Female