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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
biochemistry, genetics and molecular biology
Synteny conservation between parts of human chromosome 4q and bovine and ovine chromosomes 6
Cytogenetics and Cell Genetics, Volume 72, No. 2-3, Year 1996
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Description
Booroola Merino sheep are characterized by a high ovulation rate attributable to the presence of the FecB allele of the FEC gene. This gene, which has been assigned to sheep chromosome 6, is linked to the gene for EGF, which in man is located on the long arm of chromosome 4 (HSA 4q). To increase the number of known markers on sheep chromosome 6, we used comparative mapping data from sheep, man, and cattle. In our study, we show a synteny between EGF and the genes PDHA2 and FGF5 (from HSA 4q) and microsatelhtes ILSTS018, ILSTS090, and ILSTS093 (from bovine chromosome 6) in sheep. We also show that the conservation between HSA 4q and sheep chromosome 6 is disrupted between EGF and FGF2. © 1996 S. Karger AG, Basel.
Authors & Co-Authors
Lanneluc, I.
France, Castanet-tolosan
Inrae Occitanie-toulouse Centre
Mulsant, P.
France, Castanet-tolosan
Inrae Occitanie-toulouse Centre
Saïdi-Mehtar, Nadhira
Algeria, Oran
Université Oran 1
Elsen, J. M.
France, Castanet-tolosan
Inrae Occitanie-toulouse Centre
Statistics
Citations: 10
Authors: 4
Affiliations: 2
Identifiers
Doi:
10.1159/000134192
ISSN:
03010171
e-ISSN:
1424859X
Research Areas
Genetics And Genomics