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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Acute megakaryoblastic leukaemia with 3q inversion and elevated thrombopoietin (TSF): an autocrine role for TSF?
British Journal of Haematology, Volume 61, No. 4, Year 1985
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Description
Summary. A patient with acute megakaryoblastic leukaemia is described in whom exactly the same paracentric inversion of 3q was detected as in three previously documented cases. The patient's serum thrombopoietin (TSF) was significantly raised. Based on these findings we postulate a role for a gene (? oncogene) on chromosome 3q in thrombopoietin production. Abnormalities of 3q may assist in delineating a subgroup of acute nonlymphocytic leukaemia, namely acute megakaryoblastic leukaemia. Copyright © 1985, Wiley Blackwell. All rights reserved
Authors & Co-Authors
Pinto, Maximina Rodrigues
South Africa, Johannesburg
School of Pathology
King, M. A.
South Africa, Johannesburg
School of Pathology
Goss, Glenwood D.
South Africa, Johannesburg
University of the Witwatersrand
Bezwoda, Werner Robert
South Africa, Johannesburg
University of the Witwatersrand
Fernandes-Costa, Francisco J.
South Africa, Johannesburg
School of Pathology
Mendelow, Barry Vincent
South Africa, Johannesburg
School of Pathology
McDonald, Ted P.
United States, Chattanooga
University of Tennessee
Dowdle, Eugene B.D.
South Africa, Cape Town
University of Cape Town
Bernstein, Renée
South Africa, Johannesburg
School of Pathology
Statistics
Citations: 47
Authors: 9
Affiliations: 4
Identifiers
Doi:
10.1111/j.1365-2141.1985.tb02883.x
ISSN:
00071048
e-ISSN:
13652141
Research Areas
Genetics And Genomics
Health System And Policy