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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
biochemistry, genetics and molecular biology
Phenotypic and allelic profile of ABO and Rhésus D blood group system among blood donor in Antananarivo
International Journal of Immunogenetics, Volume 39, No. 6, Year 2012
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Description
This study assessed the phenotypic and allelic profiles of ABO and Rhesus D blood group system among first time blood donors at the National Centre of Blood Supply of Antananarivo. We collected through this retrospective study all data registered during 7years of practice (from 2003 to 2009). Age and sex were analysed with the result of ABO and RhD screening. They were tested both with Beth Vincent and Simonin tests which were performed in a plate, by using commercial monoclonal antibody (Diaclone® et Eryclone®), and home-made red cells tests. The Rh D was performed with the same commercial kits. The frequencies of alleles were calculated by using Bernstein method. Data about 45857 donors were obtained. A male predominance (80.46%) was found and most of our donors were aged <40 (74.92%). 98.90% of the donors were Rh D positive. Phenotypic distribution of each ABO antigen was, respectively, 22.61, 29.66, 6.13 and 41.60% for A, B, AB and O antigen. Allelic frequencies of A, B and O were 0.1559, 0.1987 and 0.6454. These results confirmed the fact that Madagascan population had admixed ethnic origin. © 2012 Blackwell Publishing Ltd.
Authors & Co-Authors
Randriamanantany, Zely Arivelo
Madagascar, Antananarivo
University Center Hospital of Antananarivo
Rajaonatahina, Davidra H.
Madagascar, Antananarivo
University Center Hospital of Antananarivo
Razafimanantsoa, F. É
Madagascar, Antananarivo
University Center Hospital of Antananarivo
Rasamindrakotroka, M. T.
Madagascar, Antananarivo
University Center Hospital of Antananarivo
Andriamahenina, R.
Madagascar, Antananarivo
University Center Hospital of Antananarivo
Rasoarilalamanarivo, F. B.
Madagascar, Antananarivo
Hôpital Universitaire Joseph Ravoahangy Andrianavalona
Hanitriniala, S. P.
Madagascar, Antananarivo
Hôpital Universitaire Joseph Ravoahangy Andrianavalona
Herisoa, F. R.
Madagascar, Antananarivo
Hôpital Universitaire Joseph Ravoahangy Andrianavalona
Rasamindrakotroka, Andriamiliharison Jean
Madagascar, Antananarivo
University Center Hospital of Antananarivo
Rakoto-Alson, O. A.
Madagascar, Antananarivo
University Center Hospital of Antananarivo
Statistics
Citations: 17
Authors: 10
Affiliations: 2
Identifiers
Doi:
10.1111/j.1744-313X.2012.01120.x
ISSN:
17443121
e-ISSN:
1744313X
Study Design
Cross Sectional Study
Cohort Study
Participants Gender
Male