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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
immunology and microbiology
Anal sex, vaginal practices, and HIV incidence in female sex workers in Urban Kenya: Implications for the development of intravaginal HIV prevention methods
AIDS Research and Human Retroviruses, Volume 27, No. 10, Year 2011
Notification
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Description
Multiple intravaginal HIV prevention methods, including microbicide gels, barriers, and intravaginal rings, are in clinical development in Africa. Development of intravaginal HIV prevention products requires an understanding of sexual behavior, sexually transmitted infection (STI), and vaginitis prevalences, and sexual and vaginal practices in potential target populations. We assessed these factors in a cohort of Kenyan female sex workers (FSW). Women who reported exchanging sex for money/gifts at least three times in the past month and who were HIV uninfected were enrolled and followed for 6 months. STI prevalence and HIV incidence were analyzed by multivariate logistic regression analysis, controlling for demographic and behavioral factors. Thirty-seven percent (74/200) reported having had anal sex. Frequency of anal sex was higher with regular and casual partners than with primary partners. Women were less likely to use condoms for anal sex than for vaginal sex with regular or casual partners. Vaginal washing was universal (100%). HIV incidence was 5.6 per 100 person-years (95% CI 1.62, 11.67). HIV incidence was not associated with any demographic or risk behavior. The relatively high rate of anal sex and universal vaginal washing may complicate both safety and efficacy evaluation of intravaginal products and should be taken into account in trial design. This FSW population had significant HIV incidence and needs continued HIV prevention interventions. © 2011, Mary Ann Liebert, Inc.
Authors & Co-Authors
Priddy, Frances H.
United States, Atlanta
Emory University School of Medicine
United States, New York
International Aids Vaccine Initiative
Wakasiaka, Sabina N.
Kenya, Nairobi
University of Nairobi
Hoang, Tina Dan My
United States, San Francisco
Northern California Institute for Research and Education
Smith, Donna Jo
United States, Atlanta
Georgia State University
Farah, Bashir
Kenya, Nairobi
University of Nairobi
Del Rio, Carlos D.
United States, Atlanta
Rollins School of Public Health
Ndinya-Achola, Jeckoniah O.
Kenya, Nairobi
University of Nairobi
Statistics
Citations: 46
Authors: 7
Affiliations: 6
Identifiers
Doi:
10.1089/aid.2010.0362
ISSN:
08892229
e-ISSN:
19318405
Research Areas
Infectious Diseases
Sexual And Reproductive Health
Study Design
Cross Sectional Study
Cohort Study
Study Approach
Quantitative
Study Locations
Kenya
Participants Gender
Female