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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Colorectal carcinoma in children
Journal of Pediatric Surgery, Volume 27, No. 7, Year 1992
Notification
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Description
An increasing incidence of colorectal carcinoma has been noted at this institution. We report seven children with colorectal carcinoma. The average delay between onset of symptoms and diagnosis was 4 1 2 months, and in five patients distant metastases were present at the first operation. Initial symptoms were ignored in all cases and in only one was the serious nature of the condition realized at first presentation. In five lesions the histology was mucin secreting adenocarcinoma, a poor prognostic variant. All seven died on average 11 months after diagnosis. These three factors-delay in diagnosis, advanced stage of disease, and poorly differentiated histology-contribute overall to a poor prognosis in the young. © 1992.
Authors & Co-Authors
Brown, Robin Alexander
South Africa, Cape Town
Red Cross War Memorial Children's Hospital
Rode, Heinz
South Africa, Cape Town
Red Cross War Memorial Children's Hospital
Millar, Allistair John Ward
South Africa, Cape Town
Red Cross War Memorial Children's Hospital
Sinclair-Smith, Colin Clive
South Africa, Cape Town
Red Cross War Memorial Children's Hospital
Cywes, Sidney
South Africa, Cape Town
Red Cross War Memorial Children's Hospital
Statistics
Citations: 80
Authors: 5
Affiliations: 1
Identifiers
Doi:
10.1016/0022-3468(92)90399-R
ISSN:
00223468
Research Areas
Cancer
Maternal And Child Health
Study Design
Cohort Study