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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Alcohol consumption and the risk of heart failure: the Suita Study and meta-analysis of prospective cohort studies
Environmental Health and Preventive Medicine, Volume 28, Article 26, Year 2023
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Description
Background: Alcohol consumption is a modifiable lifestyle, but its role in heart failure (HF) development is controversial. Herein, we investigated the prospective association between alcohol consumption and HF risk. Methods: A total of 2,712 participants (1,149 men and 1,563 women) from the Suita Study were followed up every two years. Cox regression was applied to calculate the hazard ratios (HRs) and 95% confidence intervals (95% CIs) of HF risk for heavy drinking (²46 g/day in men or ²23 g/day in women) and never drinking compared to light drinking (<23 g/day in men or <11.5 g/day in women). Then, we combined the results of the Suita Study with those from other eligible prospective cohort studies in a meta-analysis using the random-effects model. Results: In the Suita Study, within a median follow-up period of 8 years, 319 HF cases (162 in men and 157 in women) were detected. In men, but not women, never and heavy drinking carried a higher risk of HF than light drinking: HRs (95% CIs) = 1.65 (1.00, 2.73) and 2.14 (1.26, 3.66), respectively. Alike, the meta-analysis showed a higher risk of HF among heavy drinkers: HR (95% CI) = 1.37 (1.15, 1.62) and abstainers: HR (95% CI) = 1.18 (1.02, 1.37). Conclusion: We indicated a J-shaped association between alcohol consumption and HF risk among Japanese men. The results of the meta-analysis came in line with the Suita Study. Heavy-drinking men should be targeted for lifestyle modification interventions. © The Author(s) 2023.
Authors & Co-Authors
Arafa, Ahmed Emadeldin
Japan, Suita
National Cerebral and Cardiovascular Center
Egypt, Beni Suef
Beni-suef University
Kashima, Rena
Japan, Suita
National Cerebral and Cardiovascular Center
Japan, Suita
Osaka University
Kokubo, Yoshihiro
Japan, Suita
National Cerebral and Cardiovascular Center
Teramoto, Masayuki
Japan, Suita
National Cerebral and Cardiovascular Center
Sakai, Yukie
Japan, Suita
National Cerebral and Cardiovascular Center
Nosaka, Saya
Japan, Suita
National Cerebral and Cardiovascular Center
Kawachi, Haruna
Japan, Suita
National Cerebral and Cardiovascular Center
Japan, Suita
Osaka University
Shimamoto, Keiko
Japan, Suita
National Cerebral and Cardiovascular Center
Matsumoto, Chisa
Japan, Suita
National Cerebral and Cardiovascular Center
Japan, Tokyo
Tokyo Medical University Hospital
Gao, Qi
Japan, Suita
National Cerebral and Cardiovascular Center
Izumi, Chisato
Japan, Suita
National Cerebral and Cardiovascular Center
Statistics
Citations: 1
Authors: 11
Affiliations: 4
Identifiers
Doi:
10.1265/ehpm.22-00231
ISSN:
1342078X
Research Areas
Environmental
Substance Abuse
Study Design
Cohort Study
Study Approach
Systematic review
Participants Gender
Male
Female