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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Feasibility of using flash-heated breastmilk as an infant feeding option for HIV-exposed, uninfected infants after 6 months of age in urban Tanzania
Journal of Acquired Immune Deficiency Syndromes, Volume 60, No. 1, Year 2012
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Description
Objective: Heat-treating expressed breastmilk is recommended as an interim feeding strategy for HIV-exposed infants in resource-poor countries, but data on its feasibility are minimal. Flash-heating (FH) is a simple in-home technique for heating breastmilk that inactivates HIV although preserving its nutritional and anti-infective properties. Our primary objective was to determine, among HIV-infected mothers, the feasibility and protocol adherence of FH expressed breastmilk after 6 months of exclusive breastfeeding. Design: Prospective longitudinal. Participants: One hundred one HIV-infected breastfeeding mothers. Setting: Dar es Salaam, Tanzania. Intervention: Peer counselors provided in-home counseling and support on infant feeding from 2 to 9 months postpartum. Mothers were encouraged to exclusively breastfeed for 6 months followed by FH expressed breastmilk if her infant was HIV negative. Clinic-based staff measured infant growth and morbidity monthly, and mothers kept daily logs of infant morbidity. FH behavior was tracked until 9 months postpartum using daily logs, in-home observations, and clinic-based and home-based surveys. Bacterial cultures of unheated and heated milk samples were performed. Results: Thirty-seven of 72 eligible mothers (51.4%) chose to flash-heat. Median (range) frequency of milk expression was 3 (1-6) times daily and duration of method use on-study was 9.7 (0.1-15.6) weeks. Mean (SD) daily milk volume was 322 (201) mL (range 25-1120). No heated and 32 (30.5%) unheated samples contained bacterial pathogens. Conclusions: FH is a simple technology that many HIV-positive women can successfully use after exclusive breastfeeding to continue to provide the benefits of breastmilk while avoiding maternal-to-child transmission associated with nonexclusive breastfeeding. Based on these feasibility data, a clinical trial of the effects of FH breastmilk on infant health outcomes is warranted. Copyright © 2012 by Lippincott Williams & Wilkins.
Authors & Co-Authors
Chantry, C.
United States, Sacramento
Uc Davis Medical Center
Young, Sera L.
United States, Sacramento
Uc Davis Medical Center
Rennie, Waverly
Tanzania, Dar es Salaam
University Research Co.
Ngonyani, Monica M.
Tanzania, Dar es Salaam
University Research Co.
Mashio, Clara
Tanzania, Dar es Salaam
University Research Co.
Israel-Ballard, Kiersten A.
United States, Seattle
Path Seattle
Peerson, Janet M.
United States, Davis
University of California, Davis
Nyambo, Margaret T.
Tanzania, Dar es Salaam
University Research Co.
Matee, Mecky Isaac N.
Tanzania, Dar es Salaam
Muhimbili University of Health and Allied Sciences
Ash, Deborah M.
Unknown Affiliation
Dewey, Kathryn G.
United States, Davis
University of California, Davis
Koniz-Booher, Peggy
United States, Seattle
Path Seattle
Statistics
Citations: 14
Authors: 12
Affiliations: 5
Identifiers
Doi:
10.1097/QAI.0b013e31824fc06e
ISSN:
15254135
Research Areas
Health System And Policy
Infectious Diseases
Maternal And Child Health
Study Design
Randomised Control Trial
Cross Sectional Study
Cohort Study
Study Locations
Tanzania
Participants Gender
Female