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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Acute sporadic hepatitis e in sudanese children: Analysis based on a new western blot assay
Journal of Infectious Diseases, Volume 165, No. 6, Year 1992
Notification
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Description
A newly developed Western blot assay for antibody to hepatitis E virus (anti-HEV) was used to evaluate 39 cases of acute pediatric hepatitis and 39 control patients in Khartoum, Sudan. The mean age of cases was 6.5 years (range, 2-14); 64% were male. Acute hepatitis A (IgM anti- HAV-positive) was diagnosed in 13 cases, acute hepatitis B (IgM anti-HBc-positive) in 1, and acute hepatitis E (positive for IgM anti-HEV) in 23 (59%). None of the cases with IgM anti-HAV or IgM anti-HBc had IgM anti-HEV; 3 controls had IgM anti-HEV. Acute hepatitis E was associated with recent contact with a family member or acquaintance with jaundice and the presence of indoor plumbing. The newly developed hepatitis E assay appeared to be specific for the diagnosis of acute icteric non-A, non-B hepatitis. Hepatitis E was found to be the most common cause of acute sporadic hepatitis in children living in an urban area of Africa. © 1992 The University of Chicago.
Authors & Co-Authors
Hyams, Kenneth Craig
United States, Bethesda
Walter Reed National Military Medical Center
United States, Atlanta
Centers for Disease Control and Prevention
Sudan, Khartoum
Khartoum University
Purdy, Michael A.
United States, Bethesda
Walter Reed National Military Medical Center
United States, Atlanta
Centers for Disease Control and Prevention
Sudan, Khartoum
Khartoum University
Kaur, Manjit
United States, Bethesda
Walter Reed National Military Medical Center
United States, Atlanta
Centers for Disease Control and Prevention
Sudan, Khartoum
Khartoum University
McCarthy, Michael C.
United States, Bethesda
Walter Reed National Military Medical Center
United States, Atlanta
Centers for Disease Control and Prevention
Sudan, Khartoum
Khartoum University
Hussain, Mutwali A.M.
United States, Bethesda
Walter Reed National Military Medical Center
United States, Atlanta
Centers for Disease Control and Prevention
Sudan, Khartoum
Khartoum University
El-Tigani, Ahmed
United States, Bethesda
Walter Reed National Military Medical Center
United States, Atlanta
Centers for Disease Control and Prevention
Sudan, Khartoum
Khartoum University
Krawczyński, Krzysztof Z.
United States, Bethesda
Walter Reed National Military Medical Center
United States, Atlanta
Centers for Disease Control and Prevention
Sudan, Khartoum
Khartoum University
Bradley, Daniel W.
United States, Bethesda
Walter Reed National Military Medical Center
United States, Atlanta
Centers for Disease Control and Prevention
Sudan, Khartoum
Khartoum University
Carl, Mitchell
United States, Bethesda
Walter Reed National Military Medical Center
United States, Atlanta
Centers for Disease Control and Prevention
Sudan, Khartoum
Khartoum University
Statistics
Citations: 105
Authors: 9
Affiliations: 3
Identifiers
Doi:
10.1093/infdis/165.6.1001
ISSN:
00221899
e-ISSN:
15376613
Research Areas
Infectious Diseases
Maternal And Child Health
Study Locations
Sudan
Participants Gender
Male