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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Peritoneal dialysis in childhood acute kidney injury: Experience in southwest Nigeria
Peritoneal Dialysis International, Volume 32, No. 3, Year 2012
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Description
Background: The choices for renal replacement therapy (RRT) in childhood acute kidney injury (AKI) are limited in low-resource settings. Peritoneal dialysis (PD) appears to be the most practical modality for RRT in young children with AKI in such settings. Data from sub-Saharan Africa on the use of PD in childhood AKI are few. Methods: We performed a retrospective study of children who underwent PD for AKI at a tertiary-care hospital in southwest Nigeria from February 2004 to March 2011 (85 months). Results: The study included 27 children (55.6% female). Mean age was 3.1 ± 2.6years, with the youngest being 7 days, and the oldest, 9 years. The causes of AKI were intravascular hemolysis (n= 11), septicemia (n= 8), acute glomerulonephritis (n = 3), gastroenteritis (n = 3), and hemolytic uremic syndrome (n= 2). Peritoneal dialysis was performed manually using percutaneous or adapted catheters. Duration of PD ranged from 6 hours to 12 days (mean: 5.0 ±3.3 days). The main complications were peritonitis (n= 10), pericatheter leakage (n= 9), and catheter outflow obstruction (n= 5). Of the 27 patients, 19 (70%) survived till discharge. Conclusions: In low-resource settings, PD can be successfully performed for the management of childhood AKI. In our hospital, the use of adapted catheters may have contributed to the high complication rates. Peritoneal dialysis should be promoted for the management of childhood AKI in low-resource settings, and access to percutaneous or Tenckhoff catheters, dialysis fluid, and automated PD should be increased. © 2012 International Society for Peritoneal Dialysis.
Authors & Co-Authors
Ademola, Adebowale Dele
Nigeria, Ibadan
College of Medicine
Asinobi, Adanze Onyenonachi
Nigeria, Ibadan
College of Medicine
Ogunkunle, Oluwatoyin Oluwafunmilayo
Nigeria, Ibadan
College of Medicine
Yusuf, Bamidele Nurudeen
Nigeria, Ibadan
College of Medicine
Nigeria, Ibadan
University College Hospital, Ibadan
Ojo, Olalekan Ezekiel
Nigeria
Federal Medical Centre Nigeria
Statistics
Citations: 57
Authors: 5
Affiliations: 3
Identifiers
Doi:
10.3747/pdi.2011.00275
ISSN:
08968608
e-ISSN:
17184304
Research Areas
Health System And Policy
Maternal And Child Health
Noncommunicable Diseases
Violence And Injury
Study Design
Cohort Study
Study Locations
Nigeria
Participants Gender
Female