Frequency of cytokine polymorphisms in populations from Western Europe, Africa, Asia, the Middle East and South America

PCR-SSOP identification procedures for IL-2, IL-6, IL-10, TNF-α and TNF-β cytokine polymorphisms have been developed. Application of the procedures to a range of diverse geographically distributed populations has identified ethnic differences within the groups studied. Five populations were investigated, Northern Ireland, South African Zulu, Omani, Singapore Chinese and Mexican Mestizos. © American Society for Histocompatibility and Immunogenetics, 2002. Published by Elsevier Science Inc.