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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
Caudate lobe resection with major hepatectomy for central cholangiocarcinoma: Is it of value?
Hepato-Gastroenterology, Volume 59, No. 114, Year 2012
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Description
Background/Aims: The aim of this study was to evaluate the importance of concomitant caudate lobe resection in the course of major hepatectomy for hilar cholangiocarcinoma. Methodology: During the period between January 1995 and December 2010, 159 patients were subjected to major hepatectomy with or without total caudate lobe resection at the Gastroenterology Centre, Mansoura University. These patients were divided in two groups: 1) a caudate lobe preservation (CLP) group (79 patients) and 2) a caudate lobe resection (CLR) group (80 patients). All patient data were retrospectively reviewed. Results: This study included 94 men and 65 women with a mean age of 53.5±0 years without operative mortality. No differences were observed between groups regarding operative time, blood loss or the development of any individual postoperative complication. There were 23 (28.8%) margin-positive resections in the CLR group and 49 (62%) margin-positive resections in the CLP group (p≤0.001). Recurrence was confirmed in 53 (67.1%) and in 41(51.3%) patients in the CLP and CLR groups, respectively (p=0.031). The median survival of the CLR group was 36 months with a 5-year survival rate of 28%, while the median survival of the CLP group was 22 months with a 5-year survival rate of 5% (p≤0.001). Conclusions: Caudate lobe resection in combination with major hepatectomy did not affect operative or postoperative morbidity and mortality. However, it led to higher rates of margin-negative resections and significantly improved survival. © H.G.E. Update Medical Publishing S.A.
Authors & Co-Authors
Abd Elwahab, M. M.
Egypt, Mansoura
Gastrointestinal Surgery Center
Sultan, Ahmad M.
Egypt, Mansoura
Gastrointestinal Surgery Center
Salah, Tarek
Egypt, Mansoura
Gastrointestinal Surgery Center
Fathy, Omar Mohammed
Egypt, Mansoura
Gastrointestinal Surgery Center
ElEbidy, Gamal
Egypt, Mansoura
Gastrointestinal Surgery Center
Elshobary, Mohamed M.
Egypt, Mansoura
Gastrointestinal Surgery Center
Shiha, Usama A.
Egypt, Mansoura
Gastrointestinal Surgery Center
Rauf, Ahmed Abdul
Egypt, Mansoura
Gastrointestinal Surgery Center
Elhemaly, Mohamed
Egypt, Mansoura
Gastrointestinal Surgery Center
El-Ghawalby, Nabieh A.
Egypt, Mansoura
Gastrointestinal Surgery Center
Statistics
Citations: 30
Authors: 10
Affiliations: 1
Identifiers
Doi:
10.5754/hge11999
Research Areas
Health System And Policy
Participants Gender
Male
Female