Skip to content
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
HIV incidence and sexually transmitted disease prevalence associated with condom use: A population study in Rakai, Uganda
AIDS, Volume 15, No. 16, Year 2001
Notification
URL copied to clipboard!
Description
Objective: Evidence of condom effectiveness for HIV and sexually transmitted disease (STD) prevention is based primarily on high-risk populations. We examined condom effectiveness in a general population with high HIV prevalence in rural Africa. Methods: Data were from a randomized community trial in Rakai, Uganda. Condom usage information was obtained prospectively from 17 264 sexually active individuals aged 15-59 years over a period of 30 months. HIV incidence and STD prevalence was determined for consistent and irregular condom users, compared to non-users. Adjusted rate ratios (RR) of HIV acquisition were estimated by Poisson multivariate regression, and odds ratios of STDs estimated by logistic regression. Results: Only 4.4% reported consistent condom use and 16.5% reported inconsistent use during the prior year. Condom use was higher among males, and younger, unmarried and better educated individuals, and those reporting multiple sex partners or extramarital relationships. Consistent condom use significantly reduced HIV incidence [RR, 0.37; 95% confidence interval (Cl), 0.15-0.88], syphilis [odds ratio (OR), 0.71; 95% Cl, 0.53-0.94] and gonorrhea/Chlamydia (OR, 0.50; 95% Cl, 0.25-0.97) after adjustment for socio-demographic and behavioral characteristics. Irregular condom use was not protective against HIV or STD and was associated with increased gonorrhea/Chlamydia risk (OR, 1.44; 95% Cl, 1.06-1.99). The population attributable fraction of consistent use for prevention of HIV was -4.5% (95% Cl, -8.3 to 0.0), due to the low prevalence of consistent use in the population. Conclusions: Consistent condom use provides protection from HIV and STDs, whereas inconsistent use is not protective. Programs must emphasize consistent condom use for HIV and STD prevention. © 2001 Lippincott Williams & Wilkins.
Authors & Co-Authors
Ahmed, S. A.
United States, Baltimore
Johns Hopkins Bloomberg School of Public Health
Lutalo, Tom
Uganda, Entebbe
Uganda Virus Research Institute
Wawer, Maria J.
United States, New York
Mailman School of Public Health
Serwadda, David Musoke
Uganda, Kampala
Makerere University
Sewankambo, Nelson K.
Uganda, Kampala
Makerere University
Nalugoda, Fred Kakaire
Uganda, Entebbe
Uganda Virus Research Institute
Makumbi, Fredrick Edward
Uganda, Entebbe
Uganda Virus Research Institute
Wabwire-Mangen, Fred
Uganda, Kampala
Makerere University
Kiwanuka, Noah
Uganda, Entebbe
Uganda Virus Research Institute
Kigozi, Godfrey G.
Uganda, Entebbe
Uganda Virus Research Institute
Kiddugavu, Mohammed G.
Uganda, Entebbe
Uganda Virus Research Institute
Gray, Ronald H.
United States, Baltimore
Johns Hopkins Bloomberg School of Public Health
Statistics
Citations: 277
Authors: 12
Affiliations: 4
Identifiers
Doi:
10.1097/00002030-200111090-00013
Research Areas
Infectious Diseases
Sexual And Reproductive Health
Study Design
Cross Sectional Study
Cohort Study
Case-Control Study
Study Locations
Uganda