Purpose: Surgical-site complications (SSCs) affect patients’ clinical pathway, prolonging their hospitalization and incrementing their management costs. The present study aimed to assess the economic and organizational implications of a portable device for negative-pressure wound therapy (NPWT) implementation, compared with the administration of pharmacological therapies alone for preventing surgical complications in patients undergoing general, cardiac, obstetrical-gynecological, or orthopedic surgical procedures. Patients and methods: A total of 8,566 hospital procedures, related to the year 2015 from one hospital, were evaluated considering infection risk index, occurrence rates of SSCs, drug therapies, and surgical, diagnostic, and specialist procedures and hematological exams. Activitybased costing and budget impact analyses were implemented for the economic assessment. Results: Patients developing an SSC absorbed i) 64.27% more economic resources considering the length of stay (€ 8,269 plusmn; 2,096 versus € 5,034 plusmn; 2,901, p7 gt; 0.05) and ii) 42.43% more economic resources related to hematological and diagnostic procedures (€ 639 plusmn; 117 versus € 449 plusmn; 72, p>0.05). If the innovative device had been used over the 12-month time period, it would have decreased the risk of developing SSCs; the hospital would have realized an average reduction in health care expenditure equal to -0.69% (-€ 483,787.92) and an organizational saving in terms of length of stay equal to -1.10% (-898 days), thus allowing 95 additional procedures. Conclusion: The implementation of a portable device for NPWT would represent an effective and sustainable strategy for reducing the management costs of patients. Economic and organizational savings could be reinvested, thus i) treating a wider population and ii) reducing waiting lists, with a higher effectiveness in terms of a decrease in complications.
