Skip to content
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Visceral Leishmaniasis and HIV Coinfection in East Africa
PLoS Neglected Tropical Diseases, Volume 8, No. 6, Article e2869, Year 2014
Notification
URL copied to clipboard!
Description
Visceral Leishmaniasis (VL) is an important protozoan opportunistic disease in HIV patients in endemic areas. East Africa is second to the Indian subcontinent in the global VL caseload and first in VL-HIV coinfection rate. Because of the alteration in the disease course, the diagnostic challenges, and the poor treatment responses, VL with HIV coinfection has become a very serious challenge in East Africa today. Field experience with the use of liposomal amphotericin B in combination with miltefosine, followed by secondary prophylaxis and antiretroviral drugs, looks promising. However, this needs to be confirmed through clinical trials. Better diagnostic and follow-up methods for relapse and prediction of relapse should also be looked for. Basic research to understand the immunological interaction of the two infections may ultimately help to improve the management of the coinfection. © 2014 Diro et al.
Authors & Co-Authors
Diro, Ermias
Belgium, Antwerpen
Prins Leopold Instituut Voor Tropische Geneeskunde
Ethiopia, Gondar
University of Gondar
Lynen, Lutgarde
Belgium, Antwerpen
Prins Leopold Instituut Voor Tropische Geneeskunde
Ritmeijer, Koert
Switzerland, Geneva
Medecins Sans Frontieres
Boelaert, Marleen C.
Belgium, Antwerpen
Prins Leopold Instituut Voor Tropische Geneeskunde
Hailu, Asrat
Ethiopia, Addis Ababa
School of Medicine
van Griensven, Johan
Belgium, Antwerpen
Prins Leopold Instituut Voor Tropische Geneeskunde
Statistics
Citations: 128
Authors: 6
Affiliations: 4
Identifiers
Doi:
10.1371/journal.pntd.0002869
ISSN:
19352727
e-ISSN:
19352735
Research Areas
Infectious Diseases
Study Design
Cohort Study
Study Locations
Multi-countries