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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Interpretation and use of FRAX in clinical practice
Osteoporosis International, Volume 22, No. 9, Year 2011
Notification
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Description
Summary: The introduction of the WHO FRAX® algorithms has facilitated the assessment of fracture risk on the basis of fracture probability. Its use in fracture risk prediction has strengths, but also limitations of which the clinician should be aware and are the focus of this review Introduction: The International Osteoporosis Foundation (IOF) and the International Society for Clinical Densitometry (ISCD) appointed a joint Task Force to develop resource documents in order to make recommendations on how to improve FRAX and better inform clinicians who use FRAX. The Task Force met in November 2010 for 3 days to discuss these topics which form the focus of this review. Methods: This study reviews the resource documents and joint position statements of ISCD and IOF. Results: Details on the clinical risk factors currently used in FRAX are provided, and the reasons for the exclusion of others are provided. Recommendations are made for the development of surrogate models where country-specific FRAX models are not available. Conclusions: The wish list of clinicians for the modulation of FRAX is large, but in many instances, these wishes cannot presently be fulfilled; however, an explanation and understanding of the reasons may be helpful in translating the information provided by FRAX into clinical practice. © 2011 International Osteoporosis Foundation and National Osteoporosis Foundation.
Authors & Co-Authors
Kanis, John A.
United Kingdom, Sheffield
The Sheffield Medical School
Hans, Didier B.
Switzerland, Lausanne
Centre Hospitalier Universitaire Vaudois
Cooper, Cyrus C.
United Kingdom, Southampton
Mrc Lifecourse Epidemiology Unit
United Kingdom, Oxford
University of Oxford
Baim, S.
United States, Miami
University of Miami Leonard M. Miller School of Medicine
Bilezikian, John Paul
United States, New York
Vagelos College of Physicians and Surgeons
Binkley, N.
United States, Madison
University of Wisconsin-madison
Cauley, Jane A.
United States, Pittsburgh
University of Pittsburgh
Compston, Juliette Elizabeth
United Kingdom, Cambridge
University of Cambridge
Dawson-Hughes, Bess
United States, Boston
Jean Mayer Usda Human Nutrition Research Center on Aging
El-Hajj Fuleihan, Ghada
Lebanon, Beirut
American University of Beirut
Johansson, Helena
Sweden, Gothenburg
Sahlgrenska Akademin
Leslie, William D.
Canada, Winnipeg
University of Manitoba
Lewiecki, E. Michael
United States, Albuquerque
Unm School of Medicine
Luckey, M.
United States, Livingston
Saint Barnabas Osteoporosis and Metabolic Bone Disease Center
Odén, Anders S.
Sweden, Gothenburg
Sahlgrenska Akademin
Papapoulos, Socrates E.
Netherlands, Leiden
Leids Universitair Medisch Centrum
Poiana, C.
Romania, Bucharest
Universitatea de Medicina si Farmacie Carol Davila Din Bucuresti
Rizzoli, René R.
Switzerland, Geneva
Hôpitaux Universitaires de Genève
Wahl, D. A.
Switzerland, Nyon
International Osteoporosis Foundation, Switzerland
McCloskey, Eugene V.
United Kingdom, Sheffield
The Sheffield Medical School
Statistics
Citations: 538
Authors: 20
Affiliations: 19
Identifiers
Doi:
10.1007/s00198-011-1713-z
ISSN:
0937941X
e-ISSN:
14332965
Research Areas
Noncommunicable Diseases