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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Confirmation for a delayed inhibition of return by systematic sampling in schizophrenia
Psychiatry Research, Volume 176, No. 1, Year 2010
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Description
Inhibition of return (IOR) is a phenomenon thought to reflect a mechanism to protect the organism from redirecting attention to previously scanned insignificant locations. A number of studies reported altered IOR in schizophrenia patients with a reduction of its amplitude. However, incomplete sampling of stimulus onset asynchronies (SOAs) makes data on IOR time course incomplete. We examined 14 stabilized young patients with recent onset schizophrenia and 16 healthy controls matched for gender, age, and years of education. Schizophrenia patients (13 males, 1 female) had a mean age of 26.3 ± 5.8 years and a mean number of years of study of 9.6 ± 3.6. Their illness had a mean duration of 147 weeks. Patients displayed moderate overall slow reaction times (387 ms) in comparison with controls (322 ms). Onset of IOR was found to be delayed in schizophrenia patients appearing between 700 and 800 ms following the cue onset while it appeared at 300 ms in controls. In patients, IOR was constant up to 1100 ms; however, its amplitude was weak with an average of 6 ms. Validity effects (overall and at each SOA value) were uncorrelated to age, years of study, duration of illness, or total or subscale scores on the Positive and Negative Syndrome Scale. © 2008 Elsevier Ltd. All rights reserved.
Authors & Co-Authors
Kébir, Oussama
Tunisia, Manouba
Université de Tunis el Manar, Hôpital Razi
France, Paris
Inserm
Ben Azouz, Olfa
Tunisia, Manouba
Université de Tunis el Manar, Hôpital Razi
Rabah, Yasmine
Tunisia, Manouba
Université de Tunis el Manar, Hôpital Razi
Dellagi, Lamia
Tunisia, Manouba
Université de Tunis el Manar, Hôpital Razi
Johnson, Inès
Tunisia, Manouba
Université de Tunis el Manar, Hôpital Razi
Amado, Isabelle Reine
France, Paris
Inserm
Tabbane, Karim
Tunisia, Manouba
Université de Tunis el Manar, Hôpital Razi
Statistics
Citations: 16
Authors: 7
Affiliations: 2
Identifiers
Doi:
10.1016/j.psychres.2008.10.010
ISSN:
01651781
Research Areas
Mental Health
Participants Gender
Female