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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
Determinants of use of intermittent preventive treatment of malaria in pregnancy: Jinja, Uganda
PLoS ONE, Volume 5, No. 11, Article e15066, Year 2010
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Description
Background: Maternal malaria is associated with serious adverse pregnancy outcomes. One recommended means of preventing malaria during pregnancy is intermittent preventive therapy (IPTp) with sulfadoxine/pyrimethamine (SP). We sought to identify determinants of preventive use of SP during pregnancy among recently pregnant women in Uganda. Additionally, we characterized the timing of and indications for the administration of SP at antenatal care (ANC) visits and missed opportunities for SP administration. Methodology/Principal Findings: Utilizing a population-based random sample, we interviewed 500 women living in Jinja, Uganda who had been pregnant in the past year. Thirty-eight percent (192/500) of women received SP for the treatment of malaria and were excluded from the analysis of IPTp-SP. Of the remaining women, 275 (89.3%) reported at least two ANC visits after the first trimester and had an opportunity to receive IPTp-SP according to the Ugandan guidelines, but only 86 (31.3%) of these women received a full two-dose course of IPTp. The remaining 189 (68.7%) women missed one or more doses of IPTp-SP. Among the 168 women that were offered IPTp, 164 (97.6%) of them took the dose of SP. Conclusions/Significance: Use of IPTp in Uganda was found to be far below target levels. Our results suggest that women will take SP for IPTp if it is offered during an ANC visit. Missed opportunities to administer IPTp-SP during ANC were common in our study, suggesting provider-level improvements are needed. © 2010 Sangaré et al.
Authors & Co-Authors
Sangaré, Laura R.
Unknown Affiliation
Stergachis, Andy S.
Unknown Affiliation
Brentlinger, Paula E.
Unknown Affiliation
Richardson, Barbra Ann
Unknown Affiliation
Staedke, Sarah G.
Unknown Affiliation
Kiwuwa, Mpungu Steven
Unknown Affiliation
Weiss, Noel Scott
Unknown Affiliation
Statistics
Citations: 52
Authors: 7
Affiliations: 5
Identifiers
Doi:
10.1371/journal.pone.0015066
e-ISSN:
19326203
Research Areas
Infectious Diseases
Maternal And Child Health
Sexual And Reproductive Health
Study Design
Cross Sectional Study
Study Locations
Uganda
Participants Gender
Female