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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Maternal Recall Error in Retrospectively Reported Time-to-Pregnancy: An Assessment and Bias Analysis
Paediatric and Perinatal Epidemiology, Volume 29, No. 6, Year 2015
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Description
Background Epidemiologic studies of fecundability often use retrospectively measured time-to-pregnancy (TTP), thereby introducing potential for recall error. Little is known about how recall error affects the bias and precision of the fecundability odds ratio (FOR) in such studies. Methods Using data from the Danish Snart-Gravid Study (2007-12), we quantified error for TTP recalled in the first trimester of pregnancy relative to prospectively measured TTP among 421 women who enrolled at the start of their pregnancy attempt and became pregnant within 12 months. We defined recall error as retrospectively measured TTP minus prospectively measured TTP. Using linear regression, we assessed mean differences in recall error by maternal characteristics. We evaluated the resulting bias in the FOR and 95% confidence interval (CI) using simulation analyses that compared corrected and uncorrected retrospectively measured TTP values. Results Recall error (mean=-0.11 months, 95% CI -0.25, 0.04) was not appreciably associated with maternal age, gravidity, or recent oral contraceptive use. Women with TTP>2 months were more likely to underestimate their TTP than women with TTP≤2 months (unadjusted mean difference in error: -0.40 months, 95% CI -0.71, -0.09). FORs of recent oral contraceptive use calculated from prospectively measured, retrospectively measured, and corrected TTPs were 0.82 (95% CI 0.67, 0.99), 0.74 (95% CI 0.61, 0.90), and 0.77 (95% CI 0.62, 0.96), respectively. Conclusions Recall error was small on average among pregnancy planners who became pregnant within 12 months. Recall error biased the FOR of recent oral contraceptive use away from the null by 10%. Quantitative bias analysis of the FOR can help researchers quantify the bias from recall error. © 2015 John Wiley & Sons Ltd.
Authors & Co-Authors
Rothman, Kenneth Jay M.
United States, Boston
Boston University
United States, Research Triangle Park
Rti Health Solutions
Sørensen, Henrik Toft
United States, Boston
Boston University
Denmark, Aarhus
Aarhus Universitetshospital
Fox, Matthew P.
United States, Boston
Boston University
Statistics
Citations: 18
Authors: 3
Affiliations: 4
Identifiers
Doi:
10.1111/ppe.12245
ISSN:
02695022
Research Areas
Health System And Policy
Maternal And Child Health
Sexual And Reproductive Health
Study Design
Case-Control Study
Study Approach
Quantitative
Participants Gender
Female