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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
The role of preoperative antibiotics in the prevention of wound infection after day case surgery for inguinal hernia in children in Ile Ife, Nigeria
Pediatric Surgery International, Volume 24, No. 10, Year 2008
Notification
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Description
Purpose: Day case surgery for inguinal hernia had been an established practice of the Paediatric Surgery Unit, OAUTHC, Ile Ife for about two decades. In a retrospective review of the practice from the same center, a high incidence of postoperative wound infection was noted, which was attributed to the poor personal hygiene of the patients. This prospective study, therefore, was performed to evaluate the role of a single dose of preoperative antibiotic (using gentamicin) in the prevention of these wound infections after day case surgery for inguinal hernia in children. Methods: This was a prospective study carried out over a period of 8 months from 11 April 2004 to 20 December 2004. During this period, 88 children aged from birth to 15 years were randomized into two groups of equal numbers to undergo elective inguinal herniotomy. The children in the test group received prophylactic intravenous gentamicin, 30 min before a groin crease incision was made, while those in the control group did not. All patients were subsequently followed up for 32 days for any evidence of a wound infection. Results: There were 104 wounds in the ratio of 50:54 in the control and test groups, respectively. All 54 wounds of the children who received prophylactic gentamicin healed primarily and without complication. Five cases of wound infections occurred in the control group, giving an infection rate of 4.8% (P < 0.041). Staphylococcus aureus was the single pathogen isolated from the infected postherniotomy wounds and this organism was wholly sensitive to gentamicin. Conclusion: From the findings in this study, administration of preoperative gentamicin has a role in the prevention of wound infection after day case surgery for inguinal hernias in susceptible children. Preoperative intravenous gentamicin is therefore recommended as a prophylactic measure against wound infection after day case surgery for inguinal hernias in those children at risk of wound infection. © 2008 Springer-Verlag.
Authors & Co-Authors
Usang, Usang E.
Nigeria, Calabar
University of Calabar
Sowande, Oludayo Adedapo
Nigeria, Ife
Obafemi Awolowo University Teaching Hospitals Complex
Adejuyigbe, Olusanya A.
Nigeria, Ife
Obafemi Awolowo University Teaching Hospitals Complex
Bakare, Tajudeen Ishola Babatunde
Nigeria, Ife
Obafemi Awolowo University Teaching Hospitals Complex
Ademuyiwa, O. A.
Nigeria, Ife
Obafemi Awolowo University Teaching Hospitals Complex
Statistics
Citations: 22
Authors: 5
Affiliations: 2
Identifiers
Doi:
10.1007/s00383-008-2241-6
ISSN:
01790358
Research Areas
Health System And Policy
Maternal And Child Health
Study Design
Randomised Control Trial
Cohort Study
Study Locations
Nigeria