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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Difference in time to positivity is useful for the diagnosis of catheter-related bloodstream infection in hematopoietic stem cell transplant recipients
Bone Marrow Transplantation, Volume 35, No. 4, Year 2005
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Description
Catheter-related bloodstream infections are associated with recognized morbidity and mortality. Accurate diagnosis of such infections results in proper management of patients and in reducing unnecessary removal of catheters. We carried out a prospective study in a bone marrow transplant unit to assess the validity of a test based on the earlier positivity of central venous blood cultures in comparison with peripheral blood cultures for predicting catheter-related bacteremia. Between May 2002 and June 2004, 38 bloodstream infections with positive simultaneous central venous catheter and peripheral vein blood cultures were included. A total of 22 patients had catheter-related bacteremias and 16 had noncatheter-related bacteremias, using the catheter-tip culture/clinical criteria as the criterion standard to define catheter-related bacteremia. Differential time to positivity of 120 min or more was associated with 86% sensitivity and 87% specificity. In conclusion, differential time to positivity of 120 min or more is sensitive and specific for catheter-related bacteremia in hematopoietic stem cell transplant recipients who have nontunnelled short-term catheters. © 2005 Nature Publishing Group. All rights reserved.
Authors & Co-Authors
Abdelkefi, Abderrahman
Tunisia, Tunis
Centre National de Greffe de Moelle Osseuse
Achour, W.
Tunisia, Tunis
Centre National de Greffe de Moelle Osseuse
Ben-Othman, Tarek
Tunisia, Tunis
Centre National de Greffe de Moelle Osseuse
Torjman, Lamia
Tunisia, Tunis
Centre National de Greffe de Moelle Osseuse
Ladeb, Saloua
Tunisia, Tunis
Centre National de Greffe de Moelle Osseuse
Lakhal, Amel
Tunisia, Tunis
Centre National de Greffe de Moelle Osseuse
Hsaïri, Mohamed
Tunisia, Tunis
Institut National de Santé Publique
Kammoun, Leïla
Tunisia, Tunis
Centre National de Greffe de Moelle Osseuse
Ben Hassen, Assia B.
Tunisia, Tunis
Centre National de Greffe de Moelle Osseuse
Ben Abdeladhim, Abdeladhim
Tunisia, Tunis
Centre National de Greffe de Moelle Osseuse
Statistics
Citations: 40
Authors: 10
Affiliations: 2
Identifiers
Doi:
10.1038/sj.bmt.1704773
ISSN:
02683369
Study Design
Cohort Study