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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
chemical engineering
Chemical composition and antimicrobial activities of the essential oil of (Tunisian) Chrysanthemum trifurcatum (Desf.) Batt. and Trab. flowerheads
Comptes Rendus Chimie, Volume 11, No. 3, Year 2008
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Description
The chemical composition of essential oil isolated from the flowerheads of Chrysanthemum trifurcatum (Desf.) Batt. and Trab. var. macrocephalum (viv.) Beg. (Asteraceae) by hydrodistillation was analysed by GC and GC/MS. A total of 56 compounds representing 97.48% of the oil were identified: limonene (20.89%), γ-terpinene (19.13%), 1,8-cineole (10.64%), β-pinene (8.77%), α-pinene (5.32%), 2-hexenal (4.85%), 4-terpenyl acetate (3.42%), β-myrcene (2.31%), germacrene-B (2.01%), β-spathulenol (1.62%), longifolene (1.39%), α-cadinol (1.39%), α-thujene (1.23%) and β-bourbobene (1.06%) were found to be the major components. Essential oil of flowerheads of C. trifurcatum was tested for antibacterial activity against eight strains, using a microdilution method, and for cytotoxicity and antiviral activity against Herpes simplex virus type 1 using a neutral red incorporation method. The oil showed a great potential of antibacterial effect against Staphylococcus epidermidis and Bacillus subtilis, in the inhibition range of 64-66% and IC50 ranging from 62.5 to 125 μg/ml. On Vero cells, the CC50 of the oil was 735.9 μg/ml and it did not exhibit a significant antiviral activity. © 2007 Académie des sciences.
Authors & Co-Authors
Ben Sassi, Ahlem
Tunisia, Monastir
Faculté de Pharmacie de Monastir
Harzallah-Skhiri, Féthia
Tunisia, Monastir
Institut Supérieur de Biotechnologie de Monastir
Chraief, Imed
Tunisia, Monastir
Faculté de Médecine de Monastir
Bourgougnon, Nathalie
France, Vannes
Laboratoire de Biotechnologie et Chimie Marines Lbcm
Hammami, M. B.
Tunisia, Monastir
Faculté de Médecine de Monastir
Aouni, Mahjoub
Tunisia, Monastir
Faculté de Pharmacie de Monastir
Statistics
Citations: 25
Authors: 6
Affiliations: 4
Identifiers
Doi:
10.1016/j.crci.2007.09.006
ISSN:
16310748