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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Mortality trends in patients hospitalized with the initial acute myocardial infarction in a Middle Eastern country over 20 years
Cardiology Research and Practice, Volume 2014, Article 464323, Year 2014
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Description
We aimed to define the temporal trend in the initial Acute Myocardial Infarction (AMI) management and outcome during the last two decades in a Middle Eastern country. A total of 10,915 patients were admitted with initial AMI with mean age of 53 ± 11.8 years. Comparing the two decades (1991-2000) to (2001-2010), the use of antiplatelet drugs increased from 84% to 95%, β-blockers increased from 38% to 56%, and angiotensin converting enzyme inhibitors (ACEI) increased from 12% to 36% (P < 0.001 for all). The rates of PCI increased from 2.5% to 14.6% and thrombolytic therapy decreased from 71% to 65% (P < 0.001 for all). While the rate of hospitalization with Initial MI increased from 34% to 66%, and the average length of hospital stay decreased from 6.4 ± 3 to 4.6 ± 3, all hospital outcomes parameters improved significantly including a 39% reduction in in-hospital Mortality. Multivariate logistic regression analysis showed that higher utilization of antiplatelet drugs, β-blockers, and ACEI were the main contributors to better hospital outcomes. Over the study period, there was a significant increase in the hospitalization rate in patients presenting with initial AMI. Evidence-based medical therapies appear to be associated with a substantial improvement in outcome and in-hospital mortality. © 2014 Emad Ahmed et al.
Authors & Co-Authors
Ahmed, Emad
Qatar, Doha
Heart Hospital
Egypt, Cairo
National Heart Institute
Al Suwaidi, Jassim Mohd
Qatar, Doha
Heart Hospital
El-Menyar, Ayman Ahmed
Qatar, Doha
Weill Cornell Medicine-qatar
Qatar, Doha
Hamad Medical Corporation
Egypt, Port Said
Ahmed Maher Teaching Hospital
Albinali, Hajar A.
Qatar, Doha
Heart Hospital
Singh, Rajvir R.
Qatar, Doha
Heart Hospital
Gehani, Abdurrazzak A.
Qatar, Doha
Heart Hospital
Qatar, Doha
Weill Cornell Medicine-qatar
Statistics
Citations: 15
Authors: 6
Affiliations: 5
Identifiers
Doi:
10.1155/2014/464323
ISSN:
20908016
e-ISSN:
20900597
Research Areas
Health System And Policy
Study Approach
Quantitative