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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Mother-to-infant transmission of human immunodeficiency virus by breast milk: Presumed innocent or presumed guilty?
Clinical Infectious Diseases, Volume 15, No. 3, Year 1992
Notification
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Description
This article reviews the virological and epidemiological data available on transmission of the human immunodeficiency virus type 1 (HIV-1) by breast milk. Colostrum and breast milk are considered major modes of transmission for many animal retroviruses as well as human T-cell leukemia virus, mainly as the consequence of ingestion of infected cells. Several cases that strongly suggest transmission of HIV-1 through breast-feeding have now been reported. In addition, recent evidence suggests that postpartum HIV-1 seroconversion of a mother may be associated with a high risk of postnatal transmission to offspring via breast milk. Preventive measures such as pasteurization of breast milk have not been fully examined. While the World Health Organization continues to promote breast-feeding in areas where no safe alternative exists, the Centers for Disease Control recommends that American women who are infected by HIV-1 not practice breast-feeding if a safe alternative is available. Large-scale, carefully controlled, prospective studies of the risk of HIV-I infection associated with breast-feeding are of the utmost priority. Feasible and ethically acceptable feeding alternatives should be developed for countries where formula feeding has a strong negative effect on child morbidity and mortality. © 1992 Oxford University Press.
Authors & Co-Authors
van de Perre, Philippe
Rwanda, Kigali
Aids Reference Laboratory
Rwanda
Centre Hospitaiier de Kigali
Rwanda, Kigali
Belgian-rwandan Cooperation
United States, San Francisco
Ucsf School of Medicine
France, Bordeaux
Université de Bordeaux
Lepage, Philippe
Rwanda, Kigali
Aids Reference Laboratory
Rwanda
Centre Hospitaiier de Kigali
Rwanda, Kigali
Belgian-rwandan Cooperation
United States, San Francisco
Ucsf School of Medicine
France, Bordeaux
Université de Bordeaux
Homsy, Jacques M.
Rwanda, Kigali
Aids Reference Laboratory
Rwanda
Centre Hospitaiier de Kigali
Rwanda, Kigali
Belgian-rwandan Cooperation
United States, San Francisco
Ucsf School of Medicine
France, Bordeaux
Université de Bordeaux
Dabis, Franćois Ç.Ois
Rwanda, Kigali
Aids Reference Laboratory
Rwanda
Centre Hospitaiier de Kigali
Rwanda, Kigali
Belgian-rwandan Cooperation
United States, San Francisco
Ucsf School of Medicine
France, Bordeaux
Université de Bordeaux
Statistics
Citations: 53
Authors: 4
Affiliations: 5
Identifiers
Doi:
10.1093/clind/15.3.502
ISSN:
10584838
e-ISSN:
15376591
Research Areas
Infectious Diseases
Maternal And Child Health
Study Design
Cohort Study
Participants Gender
Female