The renin-angiotensin-aldosterone system during and after cardiopulmonary bypass
South African Medical Journal, Volume 64, No. 24, Year 1983
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Renin and aldosterone values were measured in 20 patients undergoing coronary bypass surgery. Renin activity rose to a peak during bypass, falling a little after bypass and surgery. Aldosterone levels rose significantly during bypass, and continued to do so afterwards. This demonstrates a typical physiological stress response, evoking hormonal changes.