Skip to content
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Severe pulmonary arterial hypertension as initial manifestation of intravascular lymphoma: Case report
American Journal of Hematology, Volume 79, No. 1, Year 2005
Notification
URL copied to clipboard!
Description
Intravascular lymphoma (IVL) is a rare and usually fatal disease that belongs to the class of high-grade malignant lymphomas and which is characterized by proliferation of neoplastic lymphoid cells exclusively within the lumina of small blood vessels. Its polymorphic and nonspecific clinical manifestations make antemortem diagnosis very difficult. We report herein a case of IVL revealed by fatal, precapillary, pulmonary arterial hypertension and associated with long-lasting fever. Extensive investigation of the usual causes of pulmonary arterial hypertension was negative. The diagnosis of intravascular lymphoma was made on postmortem analysis, revealing diffuse and sometimes complete obliterations of the lumina of small blood vessels by large B-cell lymphoma, including pulmonary capillaries. Thus, we propose that IVL must be added to the spectrum of etiologies of subacute pulmonary arterial hypertension, notably in the context of associated fever, both entities requiring emergency diagnosis. For this purpose, blood collected via pulmonary capillary-wedge aspiration for cytologic examination may be associated with right-sided heart catheterization when this latter procedure is suitable. © 2005 Wiley-Liss, Inc.
Authors & Co-Authors
Aouba, Achille
France, Paris
Hôpital Necker Enfants Malades
France, Paris
Hôpital Européen Georges-pompidou
Diop, Saliou N.
France, Paris
Hôpital Necker Enfants Malades
Saadoun, David
France, Paris
Hôpital Necker Enfants Malades
Vildé, Françoise
France, Paris
Hôpital Européen Georges-pompidou
Patri, Blaise
France, Paris
Hôpital Européen Georges-pompidou
Hermine, Olivier
France, Paris
Hôpital Necker Enfants Malades
Statistics
Citations: 29
Authors: 6
Affiliations: 3
Identifiers
Doi:
10.1002/ajh.20300
ISSN:
03618609
Research Areas
Cancer
Noncommunicable Diseases