Skip to content
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
Immuno-psychiatry: An agenda for clinical practice and innovative research
BMC Medicine, Volume 14, No. 1, Article 173, Year 2016
Notification
URL copied to clipboard!
Description
Background: The diagnostic scheme for psychiatric disorders is currently based purely on descriptive nomenclature given that biomarkers subtypes and clearly defined causal mechanisms are lacking for the vast majority of disorders. The emerging field of "immuno-psychiatry" has the potential to widen the exploration of a mechanism-based nosology, possibly leading to the discovery of more effective personalised treatment strategies. Discussion: Disturbances in immuno-inflammatory and related systems have been implicated in the aetiology, pathophysiology, phenomenology and comorbidity of several psychiatric disorders, including major mood disorders and schizophrenia. A fundamental challenge in their clinical management is to identify bio-signatures that might indicate risk, state, trait, prognosis or theragnosis. Here, we provide the rationale for a clinical and research agenda to refine future clinical practice and conceptual views, and to delineate pathways toward innovative treatment discovery. Conclusion: The development of bio-signatures will allow clinicians to tailor interventions to the abovementioned biomarker subtypes - a major translational goal for research in this field. © 2016 The Author(s).
Authors & Co-Authors
Leboyer, Marion
France, Creteil
Université Paris-est Créteil Val de Marne
France, Creteil
Fondamental Foundation
France, Bordeaux
Institut Interdisciplinaire de Neurosciences
Berk, Michael
Australia, Geelong
Barwon Health
Australia, Melbourne
The Florey
Australia, Melbourne
Royal Melbourne Hospital
Yolken, Robert H.
United States, Baltimore
Johns Hopkins School of Medicine
Tamouza, Ryad
France, Creteil
Fondamental Foundation
France, Paris
Inserm
France, Paris
Hôpital Saint-louis
Kupfer, David Jerome
United States, Pittsburgh
University of Pittsburgh School of Medicine
Statistics
Citations: 44
Authors: 5
Affiliations: 10
Identifiers
Doi:
10.1186/s12916-016-0712-5
ISSN:
17417015
Research Areas
Mental Health
Study Design
Cross Sectional Study
Phenomenological Study
Study Approach
Qualitative