Publication Details

AFRICAN RESEARCH NEXUS

SHINING A SPOTLIGHT ON AFRICAN RESEARCH

medicine

Effectiveness of single detachable COOK® coils in closure of the patent ductus arteriosus

Cardiovascular Journal of South Africa, Volume 15, No. 2, Year 2004

Objective: To assess the efficacy and safety of single detachable coils in the closure of PDAs. Methods: Review of cases in which a single detachable coil was implanted. The diameter of the ampulla was used to select coil size. Diameters of the PDA, ampulla and residual shunts were measured. Results: There were 36 patients with a mean minimal ductal diameter of 2.2 ± 0.6 mm. Immediately after implantation, 46% of the patients had residual shunts and after 24 hours, only 28%. A final spontaneous closure rate of 94% was observed after 21 months. There was a significant (p < 0.01) difference when minimal PDA diameter of those who had complete closure within 24 hours (median: 2 mm, interquartile range: 1.7-2.3 mm) was compared to those with a residual shunt (median: 2.5 mm, interquartile range: 2.3-3.2 mm). Negligible complications were experienced. Conclusion: Single Cook detachable coils are effective for PDA closure with a low complication rate if properly selected. There is a high rate of spontaneous closure of trivial residual shunts. In patients with a minimal ductal diameter ≥ 2 mm and a residual shunt, more coils may be considered.
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Citations: 4
Authors: 4
Affiliations: 2
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ISSN: 10159657