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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
immunology and microbiology
Periodicity and space-time clustering of severe childhood malaria on the coast of kenya
Transactions of the Royal Society of Tropical Medicine and Hygiene, Volume 87, No. 4, Year 1993
Notification
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Description
Traditionally malaria epidemiology has focused on factors such as parasite rates and vector dynamics without specific reference to disease. There are limited comprehensive data on malaria as a life-threatening event in African children. We have identified, through hospital surveillance, 581 episodes of severe malaria in residents of a defined area on the Kenya coast over a period of 3 years. This represents an absolute minimum risk of developing severe malaria by the fifth birthday of 1 in 15. The presentation of severe malaria showed marked seasonality, but the timing and magnitude of these fluctuations varied considerably between years. A satellite navigational system was used to define the exact location of the home of each severe malaria case. Space-time clustering of severe malaria was evident in this community. Seasonal peaks in incidence of severe malaria may comprise discrete mini-epidemics. In contrast, parasite rates in the community varied little during the course of the surveillance. The monitoring of disease, as opposed to parasitization, in children may result in more effective targeting of intervention resources. © 1994, Oxford University Press.
Authors & Co-Authors
Snow, Robert William
Unknown Affiliation
Peshu, Norbert M.
Unknown Affiliation
Newton, CR
Unknown Affiliation
Winstanley, P. A.
Unknown Affiliation
Mwangi, Isaiah
Unknown Affiliation
Waruiru, Catherine M.
Unknown Affiliation
Warn, P. A.
Unknown Affiliation
Marsh, K.
Unknown Affiliation
Snow, Robert W.
Unknown Affiliation
Forster, Dayo
Unknown Affiliation
Newton, Charles R.J.C.
Unknown Affiliation
Winstanley, Peter A.
Unknown Affiliation
Warn, Peter A.
Unknown Affiliation
Newbold, Chris I.
Unknown Affiliation
Marsh, Kevin
Unknown Affiliation
Schellenberg, Joanna Armstrong
Unknown Affiliation
Statistics
Citations: 157
Authors: 16
Affiliations: 4
Identifiers
Doi:
10.1016/0035-9203(93)90007-D
ISSN:
00359203
e-ISSN:
18783503
Research Areas
Health System And Policy
Infectious Diseases
Maternal And Child Health
Study Design
Randomised Control Trial
Cohort Study
Study Locations
Kenya