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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Rapid administration of crystalloid preload does not decrease the incidence of hypotension after spinal anaesthesia for elective caesarean section
British Journal of Anaesthesia, Volume 68, No. 4, Year 1992
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Description
Twenty parturients undergoing elective Caesarean section were allocated randomly to receive crystalloid preload 20 ml kg-1 over either 20 min or 10 min before spinal anaesthesia. Significant hypotension (systolic arterial pressure <100mm Hg and < 80% of baseline value) occurred in six of the 10 patients in the 20-min preload group and seven of 10 patients in the 10-min preload group (ns). Both groups had a significant (P < 0.05) increase in central venous pressure during the preload period. The mean central venous pressure in the 10-min group was 11.9 mm Hg (range 6-19 mm Hg), which was significantly greater (P < 0.05) than that in the 20-min group (mean 7.3 mm Hg, range 2-13 mm Hg). Three patients in the 10-min group had clinically unacceptable increases in central venous pressure. This study has demonstrated that rapid administration of crystalloid preload before spinal anaesthesia did not decrease the incidence or severity of hypotension, and questions the role of crystalloid preload. © 1992 British Journal Anaesthesia.
Authors & Co-Authors
Rout, Christopher Charles
South Africa, Durban
University of Kwazulu-natal
Akoojee, S. S.
South Africa, Durban
University of Kwazulu-natal
Rocke, D. Anthony
South Africa, Durban
University of Kwazulu-natal
Gouws, Eleanor
South Africa, Durban
University of Kwazulu-natal
Statistics
Citations: 149
Authors: 4
Affiliations: 1
Identifiers
Doi:
10.1093/bja/68.4.394
ISSN:
00070912
Study Design
Cohort Study