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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Low incidence of abacavir hypersensitivity reaction among african children initiating antiretroviral therapy
Pediatric Infectious Disease Journal, Volume 30, No. 6, Year 2011
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Description
Hypersensitivity reactions are reported in approximately 5% of adults receiving abacavir, but there are few published data in children. Among 1150 African children receiving antiretroviral therapy in a randomized trial, suspected hypersensitivity reactions to abacavir were rare (0.3%; 95% CI, 0.01-0.9). Patients were managed successfully through the provision of clear guidelines and education of clinical staff, children, and their caregivers. Copyright © 2011 by Lippincott Williams & Wilkins.
Authors & Co-Authors
Nahirya-Ntege, Patricia
Uganda, Entebbe
Uganda Virus Research Institute
Musiime, Victor
Uganda, Kampala
Joint Clinical Research Center Uganda
Naidoo, Bethany
United Kingdom, London
Medical Research Council
Bakeera-Kitaka, Sabrina
Uganda, Kampala
Mulago Hospital
Nathoo, Kusum Jackison
Zambia, Harare
University of Zimbabwe
Munderi, Paula
Uganda, Entebbe
Uganda Virus Research Institute
Mugyenyi, Peter N.
Uganda, Kampala
Joint Clinical Research Center Uganda
Kekitiinwa, Adeodata R.
Uganda, Kampala
Mulago Hospital
Bwakura-Dangarembizi, Mutsa F.
Zambia, Harare
University of Zimbabwe
Crawley, Jane C.
United Kingdom, London
Medical Research Council
Statistics
Citations: 10
Authors: 10
Affiliations: 5
Identifiers
Doi:
10.1097/INF.0b013e3182076864
ISSN:
08913668
e-ISSN:
15320987
Research Areas
Maternal And Child Health
Study Design
Cohort Study