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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
The changing pattern of endomyocardial fibrosis in South-West Nigeria
Clinical Medicine Insights: Cardiology, Volume 6, Year 2012
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Description
Background: Endomyocardial fibrosis (EMF) is a restrictive cardiomyopathy, the prevalence of which is declining globally. This study was carried out to determine if there were changing patterns in its local prevalence in South-West Nigeria. Methods: We reviewed the medical records of all patients admitted to or attending the cardiology clinic or medical outpatient/specialty clinics in the Department of Medicine, Ladoke Akintola University of Technology Teaching Hospital, Osogbo, South-West Nigeria. Medical data for those with EMF from January 2003 to December 2009 were retrieved and analyzed. Results: Only three cases of EMF were identified from a total of 12,794 medical patients containing a subset of 7956 cardiac patients. The prevalence of EMF was 0.02% and 0.04% for medical and cardiac patients, respectively. All the patients with EMF were in the second or third decades of life, and had right ventricular EMF and atrial fibrillation, but no eosinophilia. Conclusion: This study shows that the prevalence of EMF has declined in the study area from 10% in the 1960s and 1970s to 0.02% for medical cases and 0.04% for cardiac cases in the first decade of the 21st century. Right ventricular EMF still predominates, but without eosinophilia. Improved health care delivery's positive impact on the control of communicable diseases might be responsible for these observed changes. More work needs to be done both within and outside Nigeria to follow this trend and unravel the mystery surrounding this poorly understood cardiac disease. © the author(s), publisher and licensee Libertas Academica Ltd.
Authors & Co-Authors
Akinwusi, Patience Olayinka
Nigeria, Osogbo
Osun State University
Nigeria, Osogbo
Ladoke Akintola University Teaching Hospital
Odeyemi, Abiona Oluwadamilola
Nigeria, Osogbo
Ladoke Akintola University Teaching Hospital
Statistics
Citations: 17
Authors: 2
Affiliations: 2
Identifiers
Doi:
10.4137/CMC.S10141
Research Areas
Health System And Policy
Noncommunicable Diseases
Study Design
Cross Sectional Study
Study Locations
Nigeria