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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Impact of antimüllerian hormone assays on the outcomes of in vitro fertilization: A prospective controlled study
Fertility and Sterility, Volume 101, No. 1, Year 2014
Notification
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Description
Objective To assess the value of routine antimüllerian hormone (AMH) assays in patients considered high risk for cancellation. Design Prospective controlled study. Setting A private IVF center, Cairo, Egypt. Patient(s) In total 4,917 patients received counseling before starting IVF/intracytoplasmic sperm injection (ICSI). They were comprised of group A1 (n = 1,335), who were considered to be at risk for cancellation after ovarian stimulation, and group A2 (n = 3,582), who were considered low risk for cancellation. A control group, B (n = 4,639), included group B1 (n = 1,248) and group B2 (n = 3,391) based on the same criteria as groups A1 and A2. Intervention(s) An AMH assessment was performed for group A1. All of the patients were stimulated using the long GnRH agonist protocol. Patients with low AMH levels received the flare-up protocol. Main Outcome Measure(s) The cancellation of IVF/ICSI cycles before or after stimulation, as well as the pregnancy rates (PR) in relation to AMH levels. Result(s) The group A1 patients (6.4%) did not start IVF due to low AMH, and some (6.6%) had their cycles canceled due to poor responses, compared with 2.6% in group A2 and 13.2% in group B1. The clinical PR was 42% in patients with normal AMH and 20% in patients with low AMH. The differences among these three groups were highly significant. Conclusion(s) The AMH assays reduced the cancellations, cost, and stress experienced by couples. © 2014 by American Society for Reproductive Medicine.
Authors & Co-Authors
Aboulghar, Mohamed A.
Egypt, Cairo
Faculty of Medicine
Egypt, Cairo
The Egyptian Ivf Center
Saber, Waleed
Egypt, Cairo
Faculty of Medicine
Egypt, Cairo
The Egyptian Ivf Center
Amin, Yahia M.
Egypt, Cairo
The Egyptian Ivf Center
Aboulghar, Mona Mohamed
Egypt, Cairo
Faculty of Medicine
Egypt, Cairo
The Egyptian Ivf Center
Serour, Gamal I.
Egypt, Cairo
The Egyptian Ivf Center
Egypt, Cairo
Al-azhar University
Mansour, Ragaa T.
Egypt, Cairo
The Egyptian Ivf Center
Statistics
Citations: 18
Authors: 6
Affiliations: 3
Identifiers
Doi:
10.1016/j.fertnstert.2013.09.028
ISSN:
00150282
e-ISSN:
15565653
Research Areas
Health System And Policy
Maternal And Child Health
Sexual And Reproductive Health
Study Design
Randomised Control Trial
Cohort Study
Study Locations
Egypt