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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Utility of rapid on-site evaluation of transbronchial needle aspirates
Respiration, Volume 72, No. 2, Year 2005
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Description
Background: Rapid on-site evaluation has been proposed as a method to improve the yield of transbronchial needle aspiration. Objectives: This study investigated whether on-site analysis facilitates routine diagnostic bronchoscopy in terms of sampling, yield and cost. Methods: Patients with lesions accessible for transbronchial needle aspiration on computed tomography were investigated. A cytopathologist screened the needle aspirates on site for the presence of diagnostic material. The bronchoscopic sampling process was adjusted according to the results. In 90 consecutive patients with neoplastic disease (n = 70; 78%), non-neoplastic disease (n = 16; 18%) or undiagnosed lesions (n = 4; 4%) we aspirated 162 lung tumours or lymph node sites (mediastinal: 7%; tracheobronchial: 68%; other: 25%). In 90 consecutive patients with neoplastic disease (n = 70; 78%), non-neoplastic disease (n = 16; 18%) or undiagnosed lesions (n = 4; 4%) we aspirated 162 lung lesions (paratracheal tumours or lymph nodes: 7%; tracheobronchial lymph nodes: 68%; other: 25%). Results: The diagnostic yield of needle aspiration was 77 and 25% in patients with neoplastic and non-neoplastic lesions, respectively. Sampling could be terminated in 64% of patients after needle aspiration had been performed as the only diag-nostic modality, and on-site analysis identified diagnostic material from the first site aspirated in 50% of patients. Only in 2 patients (2%) diagnostic aspirates were not recognized on site. On-site analysis was cost effective due to savings for disposable diagnostic tools, which exceeded the extra expense for the on-site cytology service provided. Conclusions: Rapid on-site analysis of transbronchial aspirates is a highly useful, accurate and cost-effective addition to routine diagnostic bronchoscopy. Copyright © 2005 S. Karger AG.
Authors & Co-Authors
Diacon, Andreas Henri
South Africa, Tygerberg
Tygerberg Hospital
Schuurmans, Macé M.
South Africa, Tygerberg
Tygerberg Hospital
Theron, Johan
South Africa, Tygerberg
Tygerberg Hospital
Louw, Mercia
South Africa, Tygerberg
Tygerberg Hospital
Wright, Colleen Anne
South Africa, Tygerberg
Tygerberg Hospital
Brundyn, Karen
South Africa, Tygerberg
Tygerberg Hospital
Bolliger, Christoph Thomas
South Africa, Tygerberg
Tygerberg Hospital
Statistics
Citations: 165
Authors: 7
Affiliations: 1
Identifiers
Doi:
10.1159/000084050
ISSN:
00257931