Skip to content
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Clinical results and development of heterotopic ossification in total cervical disc replacement during a 4-year follow-up
European Spine Journal, Volume 19, No. 2, Year 2010
Notification
URL copied to clipboard!
Description
Cervical total disc replacement (CTDR) aims to decrease the incidence of adjacent segment disease through motion preservation in the operated disc space. Ongoing data collection and increasing number of studies describing heterotopic ossification (HO) resulting in decreased mobility of implants, forced us to carefully evaluate our long-term clinical and morphological results of patients with CTDR. We present the first 54 consecutive patients treated with 65 ProdiscC™ prostheses during a 12-month period (2/2004-3/2005). All patients signed an informed consent and were included in prospective long-term study approved by hospital ethical committee. The 1- and 2-year follow-up analysis were available for all patients included and 4-year results for 50 patients (60 implants). Clinical (neck disability index-NDI, visual analog scale-VAS) and radiological follow-up was conducted at 1-, 2- and 4-years after the procedure. The Mehren/Suchomel modification of McAfee scale was used to classify the appearance of HO. Mean preoperative NDI was 34.5%, VAS for neck pain intensity 4.6 and VAS for arm pain intensity 5.0. At 1-, 2- and 4-year follow-up, the mean NDI was 30.7, 27.2, and 30.4, mean VAS for neck pain intensity 2.5, 2.1 and 2.9 and mean VAS for arm pain intensity pain 2.2, 1.9 and 2.3, respectively. Significant HO (grade III) was present in 45% of implants and segmental ankylosis (grade IV) in another 18% 4 years after intervention. This finding had no clinical consequences and 92% of patients would undergo the same surgery again. Our clinical results (NDI, VAS) are comparable with fusion techniques. Although, advanced non-fusion technology is used, a significant frequency of HO formation and spontaneous fusion in cervical disc replacement surgery must be anticipated during long-term follow-up. © 2009 Springer-Verlag.
Authors & Co-Authors
Suchomel, Petr
Czech Republic, Liberec
Krajská Nemocnice Liberec, A.s.
Jurák, Lubomír
Czech Republic, Liberec
Krajská Nemocnice Liberec, A.s.
Beneš, Vladimír
Czech Republic, Liberec
Krajská Nemocnice Liberec, A.s.
Brabec, Radim
Czech Republic, Liberec
Krajská Nemocnice Liberec, A.s.
Bradáč, Ondřej
Czech Republic, Prague
Charles University
United Kingdom, Sheffield
Royal Hallamshire Hospital
Elgawhary, Shamel
Egypt, Zagazig
Zagazig University
Statistics
Citations: 130
Authors: 6
Affiliations: 4
Identifiers
Doi:
10.1007/s00586-009-1259-3
ISSN:
09406719
Research Areas
Disability
Health System And Policy
Study Design
Randomised Control Trial
Cohort Study
Grounded Theory