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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
immunology and microbiology
Concurrent infections in acute febrile illness patients in Egypt
American Journal of Tropical Medicine and Hygiene, Volume 77, No. 2, Year 2007
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Description
We report the occurrence of concurrent infections with multiple acute febrile illness (AFI) pathogens during an ongoing prospective laboratory-based surveillance in four infectious disease hospitals in urban and rural areas of Egypt from June 2005 to August 2006. Patients were screened for Leptospira, Rickettsia typhi, Brucella, or Salmonella enterica serogroup Typhi by various methods including serology, culture, and PCR. One hundred eighty-seven of 1,510 patients (12.4%) evaluated had supporting evidence for the presence of coinfections; 20 (1%) of these patients had 2 or more pathogens based upon confirmatory 4-fold rise in antibody titer, culture, and/or PCR. Most coinfected patients lived or worked in rural agricultural areas. The high coinfection rates suggest that defining the etiologies of AFI is imperative in guiding proper disease treatment, prevention, and control strategies in Egypt. Copyright © 2007 by The American Society of Tropical Medicine and Hygiene.
Authors & Co-Authors
Parker, Tina M.
Egypt, Cairo
U.s. Naval Medical Research Unit No. 3, Egypt
United States, New York
Us Naval Medical Research Unit No. 3
Murray, Clinton K.
United States, Fort Sam Houston
Brooke Army Medical Center
Richards, Allen L.
United States, Silver Spring
Naval Medical Research Center
Samir, Ahmed
United States, New York
Us Naval Medical Research Unit No. 3
Ismail, Tharwat F.
United States, New York
Us Naval Medical Research Unit No. 3
Fadeel, Moustafa Abdel A.
United States, New York
Us Naval Medical Research Unit No. 3
Jiang, Ju
United States, Silver Spring
Naval Medical Research Center
Wasfy, M. O.
United States, New York
Us Naval Medical Research Unit No. 3
Pimentel, Guillermo
United States, New York
Us Naval Medical Research Unit No. 3
Statistics
Citations: 66
Authors: 9
Affiliations: 4
Identifiers
Doi:
10.4269/ajtmh.2007.77.390
ISSN:
00029637
Research Areas
Health System And Policy
Infectious Diseases
Study Design
Cohort Study
Study Locations
Egypt