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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Diabetes and other disorders of glycemia in a rural South African community: Prevalence and associated risk factors
Diabetes Care, Volume 31, No. 9, Year 2008
Notification
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Description
OBJECTIVE - The purpose of this study was to determine the prevalence of diabetes, impaired glucose tolerance (IGT), impaired fasting glycemia (IFG), and associated risk factors in a rural South African black community. RESEARCH DESIGN AND METHODS - This was a cross-sectional survey conducted by random cluster sampling of adults aged >15 years. Participants had a 75-g oral glucose tolerance test using the 1998 World Health Organization criteria for disorders of glycemia. RESULTS - Of 1, 300 subjects selected, 1, 025 subjects (815 women) participated (response rate 78.9%). The overall age-adjusted prevalence of diabetes was 3.9%, IGT 4.8%, and IFG 1.5%. The prevalence was similar in men and women for diabetes (men 3.5%; women 3.9%) and IGT (men 4.6%; women 4.7%) but higher in men for IFG (men 4.0%; women 0.8%). The prevalence of diabetes and IGT increased with age both in men and women, with peak prevalence in the 55- to 64-year age-group for diabetes and in the ≥65-year age-group for IGT. Of the cases of diabetes, 84.8% were discovered during the survey. In multivariate analysis, the significant independent risk factors associated with diabetes included family history (odds ratio 3.5), alcohol ingestion (2.8), waist circumference (1.1), systolic blood pressure (1.0), serum triglycerides (2.3), and total cholesterol (1.8); hip circumference was protective (0.9). CONCLUSIONS - There is a moderate prevalence of diabetes and a high prevalence of total disorders of glycemia, which suggests that this community, unlike other rural communities in Africa, is well into an epidemic of glucose intolerance. There is a low proportion of known diabetes and a significant association with potentially modifiable risk factors. © 2008 by the American Diabetes Association.
Authors & Co-Authors
Motala, Ayesha A.
South Africa, Durban
University of Kwazulu-natal
Esterhuizen, Tonya M.
South Africa, Durban
University of Kwazulu-natal
Gouws, Eleanor
South Africa, Tygerberg
South African Medical Research Council
Pirie, Fraser J.
South Africa, Durban
University of Kwazulu-natal
Mahomed, A. K.
South Africa, Durban
University of Kwazulu-natal
Statistics
Citations: 160
Authors: 5
Affiliations: 2
Identifiers
Doi:
10.2337/dc08-0212
ISSN:
01495992
e-ISSN:
19355548
Research Areas
Health System And Policy
Noncommunicable Diseases
Substance Abuse
Study Design
Cross Sectional Study
Case-Control Study
Study Approach
Quantitative
Participants Gender
Male
Female