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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
biochemistry, genetics and molecular biology
Socioeconomic disparities in childhood cancer survival in Switzerland
International Journal of Cancer, Volume 138, No. 12, Year 2016
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Description
In this study, we investigated whether childhood cancer survival in Switzerland is influenced by socioeconomic status (SES), and if disparities vary by type of cancer and definition of SES (parental education, living condition, area-based SES). Using Cox proportional hazards models, we analyzed 5-year cumulative mortality in all patients registered in the Swiss Childhood Cancer Registry diagnosed 1991-2006 below 16 years. Information on SES was extracted from the Swiss census by probabilistic record linkage. The study included 1602 children (33% with leukemia, 20% with lymphoma, 22% with central nervous system (CNS) tumors); with an overall 5-year survival of 77% (95%CI 75-79%). Higher SES, particularly parents' education, was associated with a lower 5-year cumulative mortality. Results varied by type of cancer with no association for leukemia and particularly strong effects for CNS tumor patients, where mortality hazard ratios for the different SES indicators, comparing the highest with the lowest group, ranged from 0.48 (95%CI: 0.28-0.81) to 0.71 (95%CI: 0.44-1.15). We conclude that even in Switzerland with a high quality health care system and mandatory health insurance, socioeconomic differences in childhood cancer survival persist. Factors causing these survival differences have to be further explored, to facilitate universal access to optimal treatment and finally eliminate social inequalities in childhood cancer survival. © 2016 UICC.
Authors & Co-Authors
Rueegg, Corina Silvia
Switzerland, Bern
University of Bern
Switzerland, Luzern
Universität Luzern
Schmidlin, Kurt
Switzerland, Bern
University of Bern
Spoerri, Adrian
Switzerland, Bern
University of Bern
Niggli, F. K.
Switzerland, Zurich
Universität Zürich
Egger, Matthias
Switzerland, Bern
University of Bern
Probst-Hensch, Nicole M.
Switzerland, Allschwil
Swiss Tropical and Public Health Institute Swiss Tph
Switzerland, Basel
Universitat Basel
Zwahlen, Marcel
Switzerland, Bern
University of Bern
Kuehni, Claudia E.
Switzerland, Bern
University of Bern
Statistics
Citations: 34
Authors: 8
Affiliations: 5
Identifiers
Doi:
10.1002/ijc.30029
ISSN:
00207136
Research Areas
Cancer
Environmental
Health System And Policy
Maternal And Child Health