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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
Detection of Bocavirus in Children Suffering from Acute Respiratory Tract Infections in Saudi Arabia
PLoS ONE, Volume 8, No. 1, Article e55500, Year 2013
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Description
Human bocavirus (HBoV) was recently discovered in children with respiratory distress and/or diarrhea. To our knowledge, no previous study has reported the existence of bocavirus in Saudi Arabia. Swabs samples from 80 children with respiratory tract infections were examined for the presence of HBoV. Real-time polymerase chain reaction was used as a sensitive method to detect the HBoV. Direct gene sequencing was used to determine the genotype of the detected virus isolates. HBoV was detected in 22.5% of the examined patients. The NP1 partial gene sequence from all patients showed that the circulated strains were related to HBoV-1 genotype. Most of HBoV infected patients showed evidence of mixed coinfection with other viral pathogens. The current study clearly demonstrated that genetically conserved HBoV1 circulates in Saudi Arabia. Interestingly, most of the HBoV1 infected cases were associated with high rates of co-infections with other viruses. © 2013 Abdel-Moneim et al.
Authors & Co-Authors
Abdel-Moneim, Ahmed Sayed
Saudi Arabia, Taif
Taif University
Egypt, Beni Suef
Faculty of Veterinary Medicine
Kamel, Mahmoud M.
Saudi Arabia, Taif
Taif University
Egypt, Giza
National Cancer Institute
Al-Ghamdi, Abdullhamid S.
Saudi Arabia, Taif
Taif University
Al-Malky, Mater I.R.
Saudi Arabia, Taif
Pediatric Hospital
Statistics
Citations: 36
Authors: 4
Affiliations: 4
Identifiers
Doi:
10.1371/journal.pone.0055500
e-ISSN:
19326203
Research Areas
Genetics And Genomics
Maternal And Child Health