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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Body size and blood pressure: An analysis of Africans and the African diaspora
Epidemiology, Volume 19, No. 1, Year 2008
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Description
BACKGROUND: Blood pressure is directly and causally associated with body mass index (BMI) in populations worldwide. However, the relationship may vary across BMI in populations of African origin. METHODS: We compared the relationship between blood pressure and BMI in populations of African origin, using 13 samples from Africa, the Caribbean, the United Kingdom and the United States. We had access to data from individual participants for age, height, weight, blood pressure, and treatment of hypertension. Analysis was restricted to 18,072 participants (age 35-64 years; 44% men). We carried out multivariate regression analysis to estimate the relationship between blood pressure and BMI by country and by sex. The use of antihypertensive treatment was taken into account by exclusion and by sensitivity analysis. RESULTS: There was a positive relationship between both systolic and diastolic blood pressure and BMI. In men the slopes for systolic blood pressure varied from 0.27 mm Hg per kg/m (95% confidence interval = -0.01 to 0.56) in the United States to 1.72 mm Hg per kg/m (95% confidence interval = 0.92 to 2.53) in Ghana (Kumasi). In women, the slopes varied from 0.08 (-0.54 to 0.72) in South Africa to 1.32 (0.98 to 1.66) in the Republic of Congo. Similar variation in trends was seen for diastolic blood pressure. The higher the BMI, the shallower the slopes [-0.10 (-0.15 to -0.06) for systolic, -0.09 (-0.12 to -0.06) for diastolic]. No differences were seen after excluding persons who were being treated for hypertension. CONCLUSIONS: Blood pressure and BMI levels vary among populations of the African diaspora. The effect of BMI on blood pressure levels diminishes as BMI increases. These results suggest a complex relationship among excess body weight, adiposity, and energy expenditure. © 2008 Lippincott Williams & Wilkins, Inc.
Authors & Co-Authors
Cappuccio, Francesco Paolo
Unknown Affiliation
Kerry, Sally
Unknown Affiliation
Adeyemo, Adebowale A.
Unknown Affiliation
Luke, Amy H.
Unknown Affiliation
Amoah, Albert George Baidoe
Unknown Affiliation
Bovet, Pascal
Unknown Affiliation
Connor, Myles Dean
Unknown Affiliation
Forrester, Terrence E.
Unknown Affiliation
Gervasoni, Jean Pierre
Unknown Affiliation
Kaki, Gisela Kimbally
Unknown Affiliation
Plange-Rhule, Jacob
Unknown Affiliation
Thorogood, Margaret
Unknown Affiliation
Cooper, Richard S.
Unknown Affiliation
Statistics
Citations: 61
Authors: 13
Affiliations: 14
Identifiers
Doi:
10.1097/EDE.0b013e31815c4d2c
ISSN:
10443983
Research Areas
Health System And Policy
Noncommunicable Diseases
Study Approach
Quantitative
Study Locations
Congo
Ghana
South Africa
Participants Gender
Male
Female