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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Radioimmunoassay of Human Ligandin
Hepatology, Volume 3, No. 2, Year 1983
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Description
A sensitive and specific radioimmunoassay for human ligandin has been developed and used to study ligandin release into the serum in acute and chronic hepatitis. Serum ligandin concentrations were elevated in 67 of 68 cases of acute viral hepatitis. Ligandin levels frequently returned to normal within the first 2 weeks of illness. The rapid disappearance of ligandin preceded the return to normal of serum SGOT. In chronic active hepatitis, serum ligandin levels correlated significantly (p < 0.01) with histologic severity of disease. This correlation was not seen with SGOT. Serum ligandin may be useful in monitoring progress and the need for therapy in chronic active hepatitis. Copyright © 1983 American Association for the Study of Liver Diseases
Authors & Co-Authors
Sherman, M.
South Africa, Cape Town
University of Cape Town
Bass, Nathan Michael T.
South Africa, Cape Town
University of Cape Town
Campbell, John A.H.
South Africa, Cape Town
University of Cape Town
Kirsch, Ralph Emmanuel
South Africa, Cape Town
University of Cape Town
Statistics
Citations: 38
Authors: 4
Affiliations: 1
Identifiers
Doi:
10.1002/hep.1840030205
ISSN:
02709139
Research Areas
Infectious Diseases