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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
The impact of highly active antiretroviral therapy on activities of daily living in HIV-infected adults in South Africa
AIDS and Behavior, Volume 15, No. 4, Year 2011
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Description
This study investigated the relationship between highly active antiretroviral therapy (HAART) and instrumental activities of daily living (IADLs) among two clinical cohorts in South Africa. Between 2003 and 2008 structured questionnaires were administered to HIV-positive patients attending outpatient clinics at an urban hospital (Soweto, n = 3,081) and a rural hospital (Acornhoek, n = 1,247). Among those receiving help, an average of 4.8 and 5.1 h of assistance with IADLs daily was reported (rural and urban participants, respectively), with the patient's mother and children assisting the most. Participants on HAART were 17 and 41% less likely to receive assistance with IADLs in the rural and urban cohorts, respectively, after adjusting for demographic characteristics, healthcare utilization, and CD4 counts. HAART significantly decreased the IADL assistance among patients in South Africa. Alongside clinical benefits, HAART has the potential to reduce the burden of HIV-related care, potentially extending wider social and economic gains to other family members. © 2010 Springer Science+Business Media, LLC.
Authors & Co-Authors
Kakinami, Lisa
United States, Rochester
University of Rochester
De Bruyn, Guy
South Africa, Johannesburg
University of the Witwatersrand
Pronyk, Paul Michael
United States, New York
Columbia University
South Africa, Johannesburg
Wits School of Public Health
Mohapi, Lerato
South Africa, Johannesburg
University of the Witwatersrand
Tshabangu, Nkeko
South Africa, Johannesburg
University of the Witwatersrand
Moshabela, Mosa
South Africa, Johannesburg
Wits School of Public Health
McIntyre, James Alasdair
South Africa, Johannesburg
University of the Witwatersrand
Martinson, Neil Alexander
United States, Baltimore
Johns Hopkins University
Statistics
Citations: 21
Authors: 8
Affiliations: 5
Identifiers
Doi:
10.1007/s10461-010-9776-y
ISSN:
10907165
Research Areas
Health System And Policy
Infectious Diseases
Maternal And Child Health
Study Design
Cohort Study
Study Locations
South Africa