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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
dentistry
An assessment of orofacial clefts in Tanzania
BMC Oral Health, Volume 11, No. 1, Article 5, Year 2011
Notification
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Description
Background: Clefts of the lip (CL), the palate (CP), or both (CLP) are the most common orofacial congenital malformations found among live births, accounting for 65% of all head and neck anomalies. The frequency and pattern of orofacial clefts in different parts of the world and among different human groups varies widely. Generally, populations of Asian or Native American origin have the highest prevalence, while Caucasian populations show intermediate prevalence and African populations the lowest. To date, little is known regarding the epidemiology and pattern of orofacial clefts in Tanzania.Methods: A retrospective descriptive study was conducted at Bugando Medical Centre to identify all children with orofacial clefts that attended or were treated during a period of five years. Cleft lip and/or palate records were obtained from patient files in the Hospital's Departments of Surgery, Paediatrics and medical records. Age at presentation, sex, region of origin, type and laterality of the cleft were recorded. In addition, presence of associated congenital anomalies or syndromes was recorded.Results: A total of 240 orofacial cleft cases were seen during this period. Isolated cleft lip was the most common cleft type followed closely by cleft lip and palate (CLP). This is a departure from the pattern of clefting reported for Caucasian and Asian populations, where CLP or isolated cleft palate is the most common type. The distribution of clefts by side showed a statistically significant preponderance of the left side (43.7%) (χ2 = 92.4, p < 0.001), followed by the right (28.8%) and bilateral sides (18.3%). Patients with isolated cleft palate presented at very early age (mean age 1.00 years, SE 0.56). Associated congenital anomalies were observed in 2.8% of all patients with orofacial clefts, and included neural tube defects, Talipes and persistent ductus arteriosus.Conclusions: Unilateral orofacial clefts were significantly more common than bilateral clefts; with the left side being the most common affected side. Most of the other findings did not show marked differences with orofacial cleft distributions in other African populations. © 2011 Manyama et al; licensee BioMed Central Ltd.
Authors & Co-Authors
Manyama, Mange F.
Tanzania, Mwanza
Catholic University of Health and Allied Sciences
Canada, Calgary
University of Calgary
Rolian, Campbell
Canada, Calgary
University of Calgary
Gilyoma, Japhet M.
Tanzania, Mwanza
Bugando Medical Centre
Magori, Cassian C.
Tanzania, Mwanza
Catholic University of Health and Allied Sciences
Mjema, Kilalo M.
Tanzania, Mwanza
Catholic University of Health and Allied Sciences
Mazyala, Erick
Tanzania, Mwanza
Catholic University of Health and Allied Sciences
Kimwaga, Emmanuel A.
Tanzania, Mwanza
Catholic University of Health and Allied Sciences
Hallgrímsson, Benedikt
Canada, Calgary
University of Calgary
Statistics
Citations: 51
Authors: 8
Affiliations: 3
Identifiers
Doi:
10.1186/1472-6831-11-5
e-ISSN:
14726831
Research Areas
Health System And Policy
Maternal And Child Health
Study Design
Cross Sectional Study
Cohort Study
Study Locations
Tanzania