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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Time-dependent analysis of length of stay and mortality due to urinary tract infections in ten developing countries: INICC findings
Journal of Infection, Volume 62, No. 2, Year 2011
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Description
Objectives: To estimate the excess length of stay (LOS) and mortality in an intensive care unit (ICU) due to a Catheter associated urinary tract infections (CAUTI), using a statistical model that accounts for the timing of infection in 29 ICUs from 10 countries: Argentina, Brazil, Colombia, Greece, India, Lebanon, Mexico, Morocco, Peru, and Turkey. Methods: To estimate the extra LOS due to infection in a cohort of 69,248 admissions followed for 371,452 days in 29 ICUs, we used a multi-state model, including specific censoring to ensure that we estimate the independent effect of urinary tract infection, and not the combined effects of multiple infections. We estimated the extra length of stay and increased risk of death independently in each country, and then combined the results using a random effects meta-analysis. Results: A CAUTI prolonged length of ICU stay by an average of 1.59 days (95% CI: 0.58, 2.59 days), and increased the risk of death by 15% (95% CI: 3, 28%). Conclusions: A CAUTI leads to a small increased LOS in ICU. The increased risk of death due to CAUTI may be due to confounding with patient morbidity. © 2011 The British Infection Association.
Authors & Co-Authors
Rosenthal, Víctor Daniel
Argentina, Buenos Aires
International Nosocomial Infection Control Consortium
Dwivedy, Arpita
India, Mumbai
Dr. L. H. Hiranandani Hospital, Mumbai
Rodríguez Calderón, María Eugenia
Colombia, Bogota
Hospital la
Esen, Şaban
Turkey, Samsun
Ondokuz Mayis University, Medical School
Hernández, Héctor Torres
Mexico, Irapuato
Hospital General de Irapuato
Abouqal, Redouane
Morocco, Agdal Rabat
Ibn Sina Hospital, Agdal Rabat
Medeiros, Eduardo Alexandrino Sérvolo De
Brazil, Sao Paulo
Universidade Federal de São Paulo
Espinoza, Teodora Atencio
Peru, Pucallpa
Hospital Regional de Pucallpa
Kanj, Souha S.
Lebanon, Beirut
American University of Beirut Medical Center
Gikas, Åchilleas I.
Greece, Heraklion
Heraklion University Hospital
Barnett, Adrian G.
Greece, Heraklion
Heraklion University Hospital
Graves, Nicholas
Australia, Brisbane
Queensland University of Technology
Statistics
Citations: 39
Authors: 12
Affiliations: 11
Identifiers
Doi:
10.1016/j.jinf.2010.12.004
ISSN:
01634453
Research Areas
Health System And Policy
Study Design
Cohort Study
Study Approach
Systematic review
Study Locations
Morocco